PGR-AS1

Summary

PGR-AS1 (PGR antisense RNA 1, HGNC:52650) is a long non-coding RNA gene on chromosome 11q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52650
Approved symbol	PGR-AS1
Name	PGR antisense RNA 1
Location	11q22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AT1, AT2, AT3
Ensembl gene	ENSG00000282728
Ensembl biotype	lncRNA
Entrez	101054525
RNAcentral	URS000075D343 — lncRNA, 1223 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000531772, ENST00000632820, ENST00000843145, ENST00000843146, ENST00000843147, ENST00000843148, ENST00000843149, ENST00000843150, ENST00000843151, ENST00000843152, ENST00000843153, ENST00000843154, ENST00000843155, ENST00000843156, ENST00000843157, ENST00000843158, ENST00000843159, ENST00000843160, ENST00000843161, ENST00000843162, ENST00000843163, ENST00000843164, ENST00000843165, ENST00000843166, ENST00000843167, ENST00000843168, ENST00000843169

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000531772 — 6 exons

Exon	Start	End
ENSE00002171700	101209343	101209591
ENSE00002176353	101159159	101159255
ENSE00003777972	101130689	101130782
ENSE00003782060	101148143	101148232
ENSE00004268951	101133011	101133130
ENSE00004268958	101127317	101127438

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 82.54.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.54	gold quality
sural nerve	UBERON:0015488	78.41	gold quality
left ovary	UBERON:0002119	74.83	gold quality
ovary	UBERON:0000992	74.07	gold quality
endocervix	UBERON:0000458	71.99	gold quality
right ovary	UBERON:0002118	71.71	gold quality
popliteal artery	UBERON:0002250	71.66	gold quality
tibial artery	UBERON:0007610	71.64	gold quality
myometrium	UBERON:0001296	70.56	gold quality
body of uterus	UBERON:0009853	70.37	gold quality
uterine cervix	UBERON:0000002	69.25	gold quality
ascending aorta	UBERON:0001496	68.89	gold quality
thoracic aorta	UBERON:0001515	68.67	gold quality
ectocervix	UBERON:0012249	68.05	gold quality
stromal cell of endometrium	CL:0002255	67.05	gold quality
left coronary artery	UBERON:0001626	66.70	gold quality
right lung	UBERON:0002167	65.49	gold quality
calcaneal tendon	UBERON:0003701	65.23	gold quality
descending thoracic aorta	UBERON:0002345	65.17	gold quality
fallopian tube	UBERON:0003889	64.87	gold quality
rectum	UBERON:0001052	64.12	gold quality
smooth muscle tissue	UBERON:0001135	63.93	gold quality
left uterine tube	UBERON:0001303	63.63	gold quality
right coronary artery	UBERON:0001625	63.41	gold quality
tonsil	UBERON:0002372	63.06	gold quality
right uterine tube	UBERON:0001302	62.99	gold quality
muscle layer of sigmoid colon	UBERON:0035805	62.42	gold quality
right atrium auricular region	UBERON:0006631	62.25	gold quality
endometrium	UBERON:0001295	62.20	gold quality
colonic epithelium	UBERON:0000397	62.18	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.