PHACTR3-AS1

Summary

PHACTR3-AS1 (PHACTR3 antisense RNA 1, HGNC:40727) is a long non-coding RNA gene on chromosome 20q13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40727
Approved symbol	PHACTR3-AS1
Name	PHACTR3 antisense RNA 1
Location	20q13.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000238194
Ensembl biotype	lncRNA
Entrez	100506384
RNAcentral	URS000075DD70 — lncRNA, 678 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000443055, ENST00000451510, ENST00000663583, ENST00000668717

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443055 — 2 exons

Exon	Start	End
ENSE00001743835	59628098	59628279
ENSE00001776893	59626464	59626949

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 83.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0622 / max 7.9605, expressed in 38 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188213	0.0622	38

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	83.44	gold quality
kidney	UBERON:0002113	73.03	silver quality
putamen	UBERON:0001874	71.36	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.26	gold quality
Ammon’s horn	UBERON:0001954	69.35	gold quality
substantia nigra	UBERON:0002038	69.15	gold quality
caudate nucleus	UBERON:0001873	68.35	gold quality
temporal lobe	UBERON:0001871	67.84	gold quality
amygdala	UBERON:0001876	67.78	gold quality
primary visual cortex	UBERON:0002436	67.61	gold quality
prefrontal cortex	UBERON:0000451	66.61	gold quality
nucleus accumbens	UBERON:0001882	64.51	gold quality
frontal cortex	UBERON:0001870	63.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.92	gold quality
brain	UBERON:0000955	63.73	gold quality
cerebral cortex	UBERON:0000956	63.58	gold quality
ganglionic eminence	UBERON:0004023	62.16	gold quality
hypothalamus	UBERON:0001898	62.05	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.95	gold quality
multicellular organism	UBERON:0000468	61.81	gold quality
urinary bladder	UBERON:0001255	60.35	gold quality
superior frontal gyrus	UBERON:0002661	60.18	gold quality
right frontal lobe	UBERON:0002810	60.02	gold quality
anterior cingulate cortex	UBERON:0009835	59.03	gold quality
sural nerve	UBERON:0015488	55.74	silver quality
cerebellum	UBERON:0002037	54.28	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.25	gold quality
cerebellar cortex	UBERON:0002129	54.11	gold quality
cerebellar hemisphere	UBERON:0002245	53.83	gold quality
blood	UBERON:0000178	51.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.