PHLDA1-AS1

Summary

PHLDA1-AS1 (PHLDA1 antisense RNA 1, HGNC:55461) is a long non-coding RNA gene on chromosome 12q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55461
Approved symbol	PHLDA1-AS1
Name	PHLDA1 antisense RNA 1
Location	12q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-290L1.3
Ensembl gene	ENSG00000257453
Ensembl biotype	lncRNA
Entrez	120766149
RNAcentral	URS00000C512A — lncRNA, 569 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000552367

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000552367 — 2 exons

Exon	Start	End
ENSE00002384109	76030494	76030594
ENSE00002427644	76030911	76031378

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 92.19.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stromal cell of endometrium	CL:0002255	92.19	gold quality
sural nerve	UBERON:0015488	85.81	gold quality
lower esophagus mucosa	UBERON:0035834	85.09	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.46	silver quality
ectocervix	UBERON:0012249	73.34	gold quality
esophagus mucosa	UBERON:0002469	71.23	gold quality
cortical plate	UBERON:0005343	70.99	gold quality
ventricular zone	UBERON:0003053	70.57	gold quality
bone marrow cell	CL:0002092	69.83	silver quality
vagina	UBERON:0000996	69.68	gold quality
placenta	UBERON:0001987	69.60	gold quality
ganglionic eminence	UBERON:0004023	69.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.93	gold quality
tonsil	UBERON:0002372	67.63	gold quality
saliva-secreting gland	UBERON:0001044	67.23	gold quality
liver	UBERON:0002107	66.96	gold quality
uterine cervix	UBERON:0000002	66.89	gold quality
minor salivary gland	UBERON:0001830	66.84	gold quality
fundus of stomach	UBERON:0001160	65.33	gold quality
esophagus	UBERON:0001043	65.22	gold quality
vermiform appendix	UBERON:0001154	64.77	gold quality
adenohypophysis	UBERON:0002196	62.22	gold quality
skeletal muscle tissue	UBERON:0001134	61.49	gold quality
right adrenal gland cortex	UBERON:0035827	61.48	gold quality
bone marrow	UBERON:0002371	61.27	gold quality
tibial nerve	UBERON:0001323	61.14	gold quality
primary visual cortex	UBERON:0002436	60.74	gold quality
urinary bladder	UBERON:0001255	60.73	gold quality
stomach	UBERON:0000945	60.33	gold quality
muscle of leg	UBERON:0001383	59.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.