PIEZO1-AS1

Summary

PIEZO1-AS1 (PIEZO1 antisense RNA 1, HGNC:58065) is a long non-coding RNA gene on chromosome 16q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58065
Approved symbol	PIEZO1-AS1
Name	PIEZO1 antisense RNA 1
Location	16q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000182376
Ensembl biotype	lncRNA
Entrez	339059
RNAcentral	URS00003EF267 — lncRNA, 2137 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000333666, ENST00000567588

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000333666 — 3 exons

Exon	Start	End
ENSE00001301351	88745089	88745748
ENSE00001305098	88742767	88743490
ENSE00001329673	88743592	88744344

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 72.04.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	72.04	silver quality
bone marrow cell	CL:0002092	69.54	silver quality
cortical plate	UBERON:0005343	62.04	silver quality
tonsil	UBERON:0002372	60.05	silver quality
muscle tissue	UBERON:0002385	58.16	silver quality
ventricular zone	UBERON:0003053	57.38	silver quality
liver	UBERON:0002107	56.67	silver quality
prefrontal cortex	UBERON:0000451	56.44	gold quality
skeletal muscle tissue	UBERON:0001134	55.62	silver quality
frontal cortex	UBERON:0001870	55.31	gold quality
bone marrow	UBERON:0002371	54.84	silver quality
right frontal lobe	UBERON:0002810	54.74	gold quality
blood	UBERON:0000178	53.56	silver quality
putamen	UBERON:0001874	53.21	gold quality
urinary bladder	UBERON:0001255	53.13	silver quality
cerebral cortex	UBERON:0000956	52.99	gold quality
superior frontal gyrus	UBERON:0002661	52.91	gold quality
anterior cingulate cortex	UBERON:0009835	52.40	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.32	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	52.26	gold quality
Brodmann (1909) area 9	UBERON:0013540	51.53	gold quality
cerebellum	UBERON:0002037	51.50	gold quality
cerebellar cortex	UBERON:0002129	51.39	gold quality
cerebellar hemisphere	UBERON:0002245	51.34	gold quality
primary visual cortex	UBERON:0002436	50.89	gold quality
brain	UBERON:0000955	50.52	gold quality
caudate nucleus	UBERON:0001873	50.49	gold quality
nucleus accumbens	UBERON:0001882	49.88	gold quality
pancreas	UBERON:0001264	48.43	silver quality
kidney	UBERON:0002113	47.87	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.