PIK3CA-DT

Summary

PIK3CA-DT (PIK3CA divergent transcript, HGNC:52932) is a long non-coding RNA gene on chromosome 3q26.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52932
Approved symbol	PIK3CA-DT
Name	PIK3CA divergent transcript
Location	3q26.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229102
Ensembl biotype	lncRNA
Entrez	101928739
RNAcentral	URS00007E3D91 — lncRNA, 346 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000435560, ENST00000822433, ENST00000822434, ENST00000822435, ENST00000822436, ENST00000822437, ENST00000822438, ENST00000822439, ENST00000822440

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435560 — 3 exons

Exon	Start	End
ENSE00001721806	179101366	179101555
ENSE00001774833	179147916	179147973
ENSE00001797125	179132769	179132871

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 81.81.

Top tissues by expression

200 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.81	silver quality
calcaneal tendon	UBERON:0003701	63.27	gold quality
islet of Langerhans	UBERON:0000006	59.32	gold quality
monocyte	CL:0000576	57.52	gold quality
right lobe of liver	UBERON:0001114	54.78	gold quality
tendon	UBERON:0000043	53.95	gold quality
gastrocnemius	UBERON:0001388	53.32	gold quality
right atrium auricular region	UBERON:0006631	51.22	gold quality
pancreas	UBERON:0001264	51.08	gold quality
tibial artery	UBERON:0007610	50.82	gold quality
body of pancreas	UBERON:0001150	50.72	gold quality
upper lobe of lung	UBERON:0008948	50.44	silver quality
body of stomach	UBERON:0001161	49.65	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.54	gold quality
aorta	UBERON:0000947	48.06	gold quality
cardiac atrium	UBERON:0002081	47.74	gold quality
corpus callosum	UBERON:0002336	47.56	silver quality
left adrenal gland cortex	UBERON:0035825	47.15	gold quality
buccal mucosa cell	CL:0002336	46.75	gold quality
ascending aorta	UBERON:0001496	46.74	silver quality
prefrontal cortex	UBERON:0000451	46.57	gold quality
muscle layer of sigmoid colon	UBERON:0035805	46.44	gold quality
upper lobe of left lung	UBERON:0008952	46.36	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	46.14	gold quality
transverse colon	UBERON:0001157	46.01	gold quality
left adrenal gland	UBERON:0001234	46.01	gold quality
anterior cingulate cortex	UBERON:0009835	45.98	gold quality
ectocervix	UBERON:0012249	45.93	gold quality
omental fat pad	UBERON:0010414	45.79	gold quality
stomach	UBERON:0000945	45.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.