PIK3IP1-DT

Summary

PIK3IP1-DT (PIK3IP1 divergent transcript, HGNC:41072) is a long non-coding RNA gene on chromosome 22q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41072
Approved symbol	PIK3IP1-DT
Name	PIK3IP1 divergent transcript
Location	22q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228839
Ensembl biotype	lncRNA
Entrez	101929760
RNAcentral	URS000051BF67 — lncRNA, 422 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000440456, ENST00000451161, ENST00000726044, ENST00000726045, ENST00000726046

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440456 — 2 exons

Exon	Start	End
ENSE00001693668	31337668	31338021
ENSE00001752919	31292499	31292698

Expression profiles

Bgee: expression breadth ubiquitous, 168 present calls, max score 98.99.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1718 / max 21.4380, expressed in 62 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
191799	0.1718	62

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.99	gold quality
right testis	UBERON:0004534	78.42	gold quality
colonic epithelium	UBERON:0000397	78.22	gold quality
left testis	UBERON:0004533	77.90	gold quality
testis	UBERON:0000473	74.70	gold quality
sural nerve	UBERON:0015488	74.18	gold quality
muscle layer of sigmoid colon	UBERON:0035805	73.93	gold quality
spleen	UBERON:0002106	73.15	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.99	gold quality
small intestine Peyer’s patch	UBERON:0003454	72.72	gold quality
pancreatic ductal cell	CL:0002079	72.67	silver quality
lower esophagus muscularis layer	UBERON:0035833	72.54	gold quality
lower esophagus	UBERON:0013473	72.49	gold quality
tibial nerve	UBERON:0001323	72.44	gold quality
right lung	UBERON:0002167	72.15	gold quality
mucosa of stomach	UBERON:0001199	71.80	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.51	gold quality
minor salivary gland	UBERON:0001830	71.36	gold quality
vermiform appendix	UBERON:0001154	71.34	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	71.30	gold quality
skin of leg	UBERON:0001511	70.82	gold quality
lymph node	UBERON:0000029	70.71	gold quality
pituitary gland	UBERON:0000007	70.64	gold quality
left lobe of thyroid gland	UBERON:0001120	70.59	gold quality
tibial artery	UBERON:0007610	70.27	gold quality
adenohypophysis	UBERON:0002196	70.17	gold quality
popliteal artery	UBERON:0002250	70.17	gold quality
ventricular zone	UBERON:0003053	70.05	gold quality
right lobe of thyroid gland	UBERON:0001119	69.88	gold quality
thyroid gland	UBERON:0002046	69.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.