PIK3R5-DT

Summary

PIK3R5-DT (PIK3R5 divergent transcript, HGNC:55321) is a long non-coding RNA gene on chromosome 17p13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55321
Approved symbol	PIK3R5-DT
Name	PIK3R5 divergent transcript
Location	17p13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266389
Ensembl biotype	lncRNA
Entrez	101928235
RNAcentral	URS00026A2528 — lncRNA, 1798 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000578788, ENST00000585297, ENST00000724709, ENST00000724710

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578788 — 3 exons

Exon	Start	End
ENSE00002722301	8966767	8967841
ENSE00004047639	8976758	8976995
ENSE00004047641	8965813	8965993

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 98.89.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.62	gold quality
bone marrow cell	CL:0002092	83.11	gold quality
bone marrow	UBERON:0002371	83.06	gold quality
blood	UBERON:0000178	81.94	gold quality
monocyte	CL:0000576	80.06	gold quality
leukocyte	CL:0000738	79.97	gold quality
granulocyte	CL:0000094	77.82	gold quality
lymph node	UBERON:0000029	74.11	gold quality
vermiform appendix	UBERON:0001154	72.47	gold quality
tonsil	UBERON:0002372	72.22	gold quality
gall bladder	UBERON:0002110	70.83	gold quality
right testis	UBERON:0004534	69.85	gold quality
smooth muscle tissue	UBERON:0001135	68.75	gold quality
left testis	UBERON:0004533	68.74	gold quality
testis	UBERON:0000473	68.52	gold quality
spleen	UBERON:0002106	66.73	gold quality
duodenum	UBERON:0002114	65.76	gold quality
placenta	UBERON:0001987	62.87	gold quality
right coronary artery	UBERON:0001625	62.48	gold quality
rectum	UBERON:0001052	62.22	gold quality
right lung	UBERON:0002167	61.67	gold quality
lung	UBERON:0002048	60.11	gold quality
skeletal muscle tissue	UBERON:0001134	59.60	silver quality
upper lobe of left lung	UBERON:0008952	59.58	gold quality
islet of Langerhans	UBERON:0000006	59.23	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.50	gold quality
adipose tissue	UBERON:0001013	57.96	gold quality
prefrontal cortex	UBERON:0000451	57.87	gold quality
left coronary artery	UBERON:0001626	57.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.