PINCR

Summary

PINCR (p53-induced noncoding RNA, HGNC:53590) is a long non-coding RNA gene on chromosome Xp11.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53590
Approved symbol	PINCR
Name	p53-induced noncoding RNA
Location	Xp11.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP3-326I13.1
Ensembl gene	ENSG00000224294
Ensembl biotype	lncRNA
Entrez	101927501
RNAcentral	URS000020C1DD — lncRNA, 2228 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000440955, ENST00000758477, ENST00000758478, ENST00000758479, ENST00000758480, ENST00000758481, ENST00000758482, ENST00000758483, ENST00000758484

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440955 — 6 exons

Exon	Start	End
ENSE00001627733	43197316	43197375
ENSE00001636966	43196197	43196369
ENSE00001695176	43225030	43226598
ENSE00001703027	43176994	43177205
ENSE00001758679	43190592	43190723
ENSE00001768547	43223316	43223397

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 54.57.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1547 / max 46.1580, expressed in 53 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
196051	0.1547	53

Top tissues by expression

54 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lymph node	UBERON:0000029	54.57	gold quality
calcaneal tendon	UBERON:0003701	54.13	silver quality
thyroid gland	UBERON:0002046	49.78	silver quality
prefrontal cortex	UBERON:0000451	49.20	silver quality
blood	UBERON:0000178	49.17	gold quality
muscle of leg	UBERON:0001383	49.05	silver quality
bone marrow	UBERON:0002371	48.65	silver quality
gastrocnemius	UBERON:0001388	48.13	silver quality
lung	UBERON:0002048	47.47	silver quality
islet of Langerhans	UBERON:0000006	47.45	silver quality
urinary bladder	UBERON:0001255	46.96	gold quality
endometrium	UBERON:0001295	46.60	gold quality
pancreas	UBERON:0001264	45.57	silver quality
right ovary	UBERON:0002118	45.29	silver quality
hindlimb stylopod muscle	UBERON:0004252	44.03	silver quality
brain	UBERON:0000955	43.98	silver quality
saliva-secreting gland	UBERON:0001044	43.83	silver quality
myometrium	UBERON:0001296	43.16	silver quality
body of pancreas	UBERON:0001150	42.83	silver quality
upper lobe of left lung	UBERON:0008952	42.75	silver quality
heart left ventricle	UBERON:0002084	42.39	silver quality
body of uterus	UBERON:0009853	41.67	silver quality
tibial artery	UBERON:0007610	41.52	silver quality
rectum	UBERON:0001052	41.47	silver quality
left coronary artery	UBERON:0001626	40.81	silver quality
small intestine	UBERON:0002108	40.57	silver quality
prostate gland	UBERON:0002367	40.47	silver quality
ovary	UBERON:0000992	40.22	silver quality
ascending aorta	UBERON:0001496	40.08	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	39.59	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.