PIWIL2-DT

Summary

PIWIL2-DT (PIWIL2 divergent transcript, HGNC:55522) is a long non-coding RNA gene on chromosome 8p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55522
Approved symbol	PIWIL2-DT
Name	PIWIL2 divergent transcript
Location	8p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254064
Ensembl biotype	lncRNA
Entrez	100507071
RNAcentral	URS0000A76CDB — lncRNA, 528 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000523556, ENST00000822414, ENST00000822415

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000523556 — 2 exons

Exon	Start	End
ENSE00004230206	22274979	22275329
ENSE00004230211	22254504	22254906

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 93.45.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.45	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.62	gold quality
left testis	UBERON:0004533	78.16	gold quality
testis	UBERON:0000473	77.85	gold quality
right testis	UBERON:0004534	77.17	gold quality
stromal cell of endometrium	CL:0002255	76.86	gold quality
gastrocnemius	UBERON:0001388	76.54	gold quality
muscle of leg	UBERON:0001383	75.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.66	gold quality
cortical plate	UBERON:0005343	74.61	gold quality
ganglionic eminence	UBERON:0004023	74.49	gold quality
skeletal muscle tissue	UBERON:0001134	72.88	gold quality
right coronary artery	UBERON:0001625	72.73	gold quality
prefrontal cortex	UBERON:0000451	72.32	gold quality
ventricular zone	UBERON:0003053	71.80	gold quality
primary visual cortex	UBERON:0002436	71.58	gold quality
cerebellum	UBERON:0002037	71.23	gold quality
cerebellar cortex	UBERON:0002129	71.16	gold quality
cerebellar hemisphere	UBERON:0002245	71.12	gold quality
smooth muscle tissue	UBERON:0001135	71.00	gold quality
superior frontal gyrus	UBERON:0002661	70.93	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.85	gold quality
sural nerve	UBERON:0015488	70.61	gold quality
ovary	UBERON:0000992	70.49	gold quality
left ovary	UBERON:0002119	70.49	gold quality
frontal cortex	UBERON:0001870	70.36	gold quality
lower esophagus muscularis layer	UBERON:0035833	70.16	gold quality
lower esophagus	UBERON:0013473	70.13	gold quality
endometrium	UBERON:0001295	69.93	gold quality
right ovary	UBERON:0002118	69.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.