PKD1-AS1

Summary

PKD1-AS1 (PKD1 antisense RNA 1, HGNC:56035) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56035
Approved symbol	PKD1-AS1
Name	PKD1 antisense RNA 1
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	LUCRC
Ensembl gene	ENSG00000259933
Ensembl biotype	lncRNA
Entrez	105371049
RNAcentral	URS00001AB7B8 — lncRNA, 600 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000563284, ENST00000570072

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563284 — 4 exons

Exon	Start	End
ENSE00002583301	2095343	2095433
ENSE00002591766	2092889	2093012
ENSE00002608815	2091539	2091608
ENSE00002619400	2094721	2094941

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 91.72.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	91.72	gold quality
cerebellar hemisphere	UBERON:0002245	89.90	gold quality
cerebellar cortex	UBERON:0002129	89.84	gold quality
cerebellum	UBERON:0002037	89.83	gold quality
mucosa of transverse colon	UBERON:0004991	89.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.61	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.36	gold quality
pituitary gland	UBERON:0000007	82.57	gold quality
ascending aorta	UBERON:0001496	81.19	gold quality
descending thoracic aorta	UBERON:0002345	81.16	gold quality
transverse colon	UBERON:0001157	80.96	gold quality
thoracic aorta	UBERON:0001515	80.91	gold quality
adenohypophysis	UBERON:0002196	80.56	gold quality
right frontal lobe	UBERON:0002810	80.03	gold quality
colon	UBERON:0001155	78.55	gold quality
body of uterus	UBERON:0009853	78.38	gold quality
popliteal artery	UBERON:0002250	78.21	gold quality
tibial artery	UBERON:0007610	78.17	gold quality
muscle layer of sigmoid colon	UBERON:0035805	77.80	gold quality
intestine	UBERON:0000160	77.49	gold quality
right uterine tube	UBERON:0001302	77.34	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	77.34	gold quality
superior frontal gyrus	UBERON:0002661	76.80	gold quality
mucosa of stomach	UBERON:0001199	76.72	gold quality
left ovary	UBERON:0002119	76.66	gold quality
myometrium	UBERON:0001296	76.65	gold quality
apex of heart	UBERON:0002098	76.50	gold quality
primary visual cortex	UBERON:0002436	76.48	gold quality
right ovary	UBERON:0002118	76.44	gold quality
frontal cortex	UBERON:0001870	76.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.