PKD2L2-DT

Summary

PKD2L2-DT (PKD2L2 divergent transcript, HGNC:55557) is a long non-coding RNA gene on chromosome 5q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55557
Approved symbol	PKD2L2-DT
Name	PKD2L2 divergent transcript
Location	5q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250159
Ensembl biotype	lncRNA
Entrez	101928005
RNAcentral	URS0000EEFE9C — lncRNA, 5227 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 53 — 53 lncRNA

ENST00000508281, ENST00000514616, ENST00000661977, ENST00000666934, ENST00000670115, ENST00000728404, ENST00000728405, ENST00000728406, ENST00000728407, ENST00000728408, ENST00000728409, ENST00000728410, ENST00000728411, ENST00000728412, ENST00000728413, ENST00000728414, ENST00000728415, ENST00000728416, ENST00000728417, ENST00000728418, ENST00000728419, ENST00000728420, ENST00000728421, ENST00000728422, ENST00000728423, ENST00000728424, ENST00000728425, ENST00000728426, ENST00000728427, ENST00000728428, ENST00000728429, ENST00000728430, ENST00000728431, ENST00000728432, ENST00000728433, ENST00000728434, ENST00000728435, ENST00000728436, ENST00000728437, ENST00000728438, ENST00000728439, ENST00000728440, ENST00000728441, ENST00000728442, ENST00000728443, ENST00000728444, ENST00000728445, ENST00000728446, ENST00000728447, ENST00000728448, ENST00000728449, ENST00000728450, ENST00000728451

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508281 — 3 exons

Exon	Start	End
ENSE00002034220	137888160	137888288
ENSE00002058552	137879724	137883621
ENSE00003885331	137889147	137889394

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 88.49.

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	88.49	gold quality
hindlimb stylopod muscle	UBERON:0004252	87.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.91	gold quality
corpus callosum	UBERON:0002336	83.07	gold quality
muscle tissue	UBERON:0002385	81.19	gold quality
muscle of leg	UBERON:0001383	80.98	gold quality
gastrocnemius	UBERON:0001388	79.77	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.97	gold quality
apex of heart	UBERON:0002098	77.52	gold quality
heart left ventricle	UBERON:0002084	77.29	gold quality
calcaneal tendon	UBERON:0003701	74.56	gold quality
heart	UBERON:0000948	74.21	gold quality
right atrium auricular region	UBERON:0006631	73.27	gold quality
sural nerve	UBERON:0015488	73.18	gold quality
adrenal tissue	UBERON:0018303	73.14	gold quality
bone marrow cell	CL:0002092	71.33	silver quality
adrenal gland	UBERON:0002369	70.15	gold quality
right adrenal gland cortex	UBERON:0035827	69.70	gold quality
left adrenal gland	UBERON:0001234	69.64	gold quality
right adrenal gland	UBERON:0001233	69.40	gold quality
left adrenal gland cortex	UBERON:0035825	69.23	gold quality
duodenum	UBERON:0002114	68.75	gold quality
cerebellar vermis	UBERON:0004720	68.65	gold quality
colonic epithelium	UBERON:0000397	68.64	silver quality
tonsil	UBERON:0002372	67.88	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.87	gold quality
spinal cord	UBERON:0002240	66.81	gold quality
bone marrow	UBERON:0002371	65.69	gold quality
substantia nigra	UBERON:0002038	65.48	gold quality
small intestine	UBERON:0002108	65.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.