PKIA-AS1

Summary

PKIA-AS1 (PKIA antisense RNA 1, HGNC:51659) is a long non-coding RNA gene on chromosome 8q21.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51659
Approved symbol	PKIA-AS1
Name	PKIA antisense RNA 1
Location	8q21.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254266
Ensembl biotype	lncRNA
Entrez	101927003
RNAcentral	URS00007E4AE0 — lncRNA, 2029 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000519242, ENST00000522302, ENST00000522807, ENST00000653339, ENST00000669183, ENST00000720941, ENST00000720942, ENST00000720943, ENST00000720944, ENST00000720945, ENST00000720946, ENST00000720947, ENST00000720948

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000519242 — 4 exons

Exon	Start	End
ENSE00002099052	78556499	78556599
ENSE00002105387	78535850	78535973
ENSE00002109178	78558424	78558497
ENSE00002120707	78535026	78535721

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 90.21.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0368 / max 16.1964, expressed in 8 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93655	0.0368	8

Top tissues by expression

215 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
secondary oocyte	CL:0000655	90.21	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.99	gold quality
oocyte	CL:0000023	80.99	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.48	gold quality
sural nerve	UBERON:0015488	69.05	gold quality
adrenal tissue	UBERON:0018303	63.23	gold quality
ganglionic eminence	UBERON:0004023	60.54	gold quality
ventricular zone	UBERON:0003053	58.43	silver quality
gall bladder	UBERON:0002110	57.52	gold quality
testis	UBERON:0000473	57.20	gold quality
right testis	UBERON:0004534	57.19	gold quality
cortical plate	UBERON:0005343	56.81	silver quality
left testis	UBERON:0004533	56.68	gold quality
stromal cell of endometrium	CL:0002255	54.48	silver quality
vermiform appendix	UBERON:0001154	52.46	gold quality
calcaneal tendon	UBERON:0003701	52.17	silver quality
sperm	CL:0000019	51.63	silver quality
islet of Langerhans	UBERON:0000006	51.45	gold quality
corpus callosum	UBERON:0002336	51.25	gold quality
prefrontal cortex	UBERON:0000451	50.71	gold quality
hindlimb stylopod muscle	UBERON:0004252	50.65	silver quality
adrenal gland	UBERON:0002369	49.53	gold quality
monocyte	CL:0000576	49.34	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	49.22	gold quality
right atrium auricular region	UBERON:0006631	48.99	gold quality
pancreas	UBERON:0001264	48.97	gold quality
cardiac atrium	UBERON:0002081	48.66	gold quality
blood	UBERON:0000178	48.24	gold quality
left ovary	UBERON:0002119	48.24	gold quality
heart	UBERON:0000948	48.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.