PKNOX2-AS1

Summary

PKNOX2-AS1 (PKNOX2 antisense RNA 1, HGNC:56709) is a long non-coding RNA gene on chromosome 11q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56709
Approved symbol	PKNOX2-AS1
Name	PKNOX2 antisense RNA 1
Location	11q24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP001007.1
Ensembl gene	ENSG00000254932
Ensembl biotype	lncRNA
Entrez	105369549
RNAcentral	URS000031754D — lncRNA, 645 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000526796

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526796 — 2 exons

Exon	Start	End
ENSE00002151418	125266640	125266798
ENSE00002171481	125258626	125259111

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 67.63.

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	67.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.46	gold quality
colonic epithelium	UBERON:0000397	62.70	silver quality
descending thoracic aorta	UBERON:0002345	60.40	gold quality
liver	UBERON:0002107	58.87	silver quality
uterine cervix	UBERON:0000002	54.69	gold quality
sural nerve	UBERON:0015488	54.20	silver quality
adrenal tissue	UBERON:0018303	53.41	gold quality
lung	UBERON:0002048	51.33	gold quality
right lobe of liver	UBERON:0001114	50.63	silver quality
right atrium auricular region	UBERON:0006631	50.57	gold quality
ectocervix	UBERON:0012249	50.50	gold quality
fundus of stomach	UBERON:0001160	50.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.11	gold quality
left ovary	UBERON:0002119	49.72	gold quality
left coronary artery	UBERON:0001626	49.66	gold quality
placenta	UBERON:0001987	49.50	gold quality
superior frontal gyrus	UBERON:0002661	49.44	silver quality
endocervix	UBERON:0000458	49.27	gold quality
ovary	UBERON:0000992	49.12	gold quality
corpus callosum	UBERON:0002336	48.99	gold quality
upper lobe of left lung	UBERON:0008952	48.99	gold quality
prefrontal cortex	UBERON:0000451	48.84	gold quality
myometrium	UBERON:0001296	48.67	gold quality
heart	UBERON:0000948	48.62	gold quality
muscle of leg	UBERON:0001383	48.43	gold quality
adrenal gland	UBERON:0002369	48.31	gold quality
small intestine	UBERON:0002108	48.20	gold quality
ascending aorta	UBERON:0001496	48.10	gold quality
left testis	UBERON:0004533	47.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.