PKNOX2-DT

Summary

PKNOX2-DT (PKNOX2 divergent transcript, HGNC:50690) is a long non-coding RNA gene on chromosome 11q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50690
Approved symbol	PKNOX2-DT
Name	PKNOX2 divergent transcript
Location	11q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254880
Ensembl biotype	lncRNA
Entrez	103695364
RNAcentral	URS00000829DF — lncRNA, 586 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000532316

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532316 — 3 exons

Exon	Start	End
ENSE00002166425	125160546	125160648
ENSE00002167047	125164341	125164609
ENSE00002178651	125158461	125158674

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 62.27.

Top tissues by expression

97 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	62.27	gold quality
gall bladder	UBERON:0002110	57.01	gold quality
prefrontal cortex	UBERON:0000451	56.91	gold quality
primary visual cortex	UBERON:0002436	55.12	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.21	gold quality
frontal cortex	UBERON:0001870	53.77	gold quality
liver	UBERON:0002107	53.36	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	52.92	gold quality
left uterine tube	UBERON:0001303	52.40	gold quality
islet of Langerhans	UBERON:0000006	51.81	gold quality
vermiform appendix	UBERON:0001154	51.76	gold quality
lymph node	UBERON:0000029	51.75	gold quality
blood	UBERON:0000178	51.64	gold quality
placenta	UBERON:0001987	51.64	gold quality
cerebral cortex	UBERON:0000956	51.63	gold quality
superior frontal gyrus	UBERON:0002661	51.29	gold quality
right frontal lobe	UBERON:0002810	51.08	gold quality
smooth muscle tissue	UBERON:0001135	49.85	gold quality
urinary bladder	UBERON:0001255	49.56	gold quality
brain	UBERON:0000955	48.97	gold quality
cerebellum	UBERON:0002037	48.74	silver quality
cerebellar cortex	UBERON:0002129	48.71	silver quality
cerebellar hemisphere	UBERON:0002245	48.53	silver quality
right hemisphere of cerebellum	UBERON:0014890	48.29	silver quality
nucleus accumbens	UBERON:0001882	48.25	gold quality
pituitary gland	UBERON:0000007	47.61	gold quality
ovary	UBERON:0000992	47.58	gold quality
anterior cingulate cortex	UBERON:0009835	47.56	gold quality
muscle of leg	UBERON:0001383	47.41	gold quality
left ovary	UBERON:0002119	47.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.