PKP4-AS1

Summary

PKP4-AS1 (PKP4 antisense RNA 1, HGNC:52580) is a long non-coding RNA gene on chromosome 2q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52580
Approved symbol	PKP4-AS1
Name	PKP4 antisense RNA 1
Location	2q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000204380
Ensembl biotype	lncRNA
Entrez	100129029
RNAcentral	URS000033C7A1 — lncRNA, 4067 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000342892, ENST00000442666, ENST00000629904, ENST00000846985, ENST00000846986, ENST00000846987

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000342892 — 4 exons

Exon	Start	End
ENSE00001467621	158658337	158661750
ENSE00001467622	158665848	158666081
ENSE00001467624	158679246	158679389
ENSE00001467625	158734728	158735002

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 85.63.

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
secondary oocyte	CL:0000655	85.63	gold quality
oocyte	CL:0000023	83.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.36	gold quality
minor salivary gland	UBERON:0001830	75.04	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	74.08	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.75	gold quality
saliva-secreting gland	UBERON:0001044	73.55	gold quality
cerebellar hemisphere	UBERON:0002245	73.06	gold quality
cerebellar cortex	UBERON:0002129	72.89	gold quality
metanephros cortex	UBERON:0010533	72.41	gold quality
lower esophagus mucosa	UBERON:0035834	71.69	gold quality
buccal mucosa cell	CL:0002336	71.50	gold quality
spinal cord	UBERON:0002240	71.03	gold quality
mouth mucosa	UBERON:0003729	70.80	gold quality
cerebellum	UBERON:0002037	70.59	gold quality
right uterine tube	UBERON:0001302	70.58	gold quality
parotid gland	UBERON:0001831	69.13	gold quality
right lobe of thyroid gland	UBERON:0001119	69.08	gold quality
tendon of biceps brachii	UBERON:0008188	68.63	silver quality
left lobe of thyroid gland	UBERON:0001120	68.31	gold quality
colonic epithelium	UBERON:0000397	68.11	silver quality
bone marrow cell	CL:0002092	68.02	silver quality
thyroid gland	UBERON:0002046	67.29	gold quality
vagina	UBERON:0000996	66.41	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.35	gold quality
esophagus mucosa	UBERON:0002469	66.07	gold quality
right frontal lobe	UBERON:0002810	65.42	gold quality
ectocervix	UBERON:0012249	65.35	gold quality
endocervix	UBERON:0000458	65.01	gold quality
uterine cervix	UBERON:0000002	64.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.