PLA2G4C-AS1

Summary

PLA2G4C-AS1 (PLA2G4C antisense RNA 1, HGNC:51585) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51585
Approved symbol	PLA2G4C-AS1
Name	PLA2G4C antisense RNA 1
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269420
Ensembl biotype	lncRNA
Entrez	106144526
RNAcentral	URS00008E39AF — lncRNA, 625 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000596552, ENST00000601548, ENST00000601950

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000596552 — 5 exons

Exon	Start	End
ENSE00002992182	48064750	48064945
ENSE00003015733	48061618	48061688
ENSE00003036520	48063830	48063923
ENSE00003146378	48061884	48062039
ENSE00003202710	48061428	48061478

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 82.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0528 / max 47.5130, expressed in 3 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
176745	0.0246	2
176747	0.0171	3
176746	0.0090	3
176748	0.0020	2

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.94	silver quality
apex of heart	UBERON:0002098	71.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.68	gold quality
skeletal muscle tissue	UBERON:0001134	68.01	gold quality
bone marrow cell	CL:0002092	65.70	silver quality
muscle of leg	UBERON:0001383	64.80	gold quality
gastrocnemius	UBERON:0001388	64.35	gold quality
mucosa of stomach	UBERON:0001199	63.88	gold quality
stromal cell of endometrium	CL:0002255	63.02	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	62.31	gold quality
prefrontal cortex	UBERON:0000451	61.09	gold quality
substantia nigra	UBERON:0002038	60.15	gold quality
heart left ventricle	UBERON:0002084	59.68	gold quality
monocyte	CL:0000576	59.38	gold quality
lymph node	UBERON:0000029	59.20	gold quality
primary visual cortex	UBERON:0002436	59.20	gold quality
right adrenal gland cortex	UBERON:0035827	59.19	gold quality
granulocyte	CL:0000094	58.56	gold quality
left adrenal gland cortex	UBERON:0035825	57.80	gold quality
frontal cortex	UBERON:0001870	57.72	gold quality
Ammon’s horn	UBERON:0001954	57.72	gold quality
left adrenal gland	UBERON:0001234	57.49	gold quality
cerebellum	UBERON:0002037	57.34	gold quality
cerebellar cortex	UBERON:0002129	57.23	gold quality
cerebellar hemisphere	UBERON:0002245	57.22	gold quality
heart	UBERON:0000948	57.17	gold quality
adrenal gland	UBERON:0002369	57.13	gold quality
cortex of kidney	UBERON:0001225	57.01	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.78	gold quality
cerebral cortex	UBERON:0000956	56.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.