PLA2G4E-AS1

Summary

PLA2G4E-AS1 (PLA2G4E antisense RNA 1, HGNC:51419) is a long non-coding RNA gene on chromosome 15q15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51419
Approved symbol	PLA2G4E-AS1
Name	PLA2G4E antisense RNA 1
Location	15q15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246740
Ensembl biotype	lncRNA
Entrez	101928388
RNAcentral	URS0000432B41 — lncRNA, 2499 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000499478, ENST00000729102, ENST00000729103, ENST00000729104, ENST00000729105, ENST00000729106, ENST00000729107

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499478 — 4 exons

Exon	Start	End
ENSE00001961384	41997139	41999094
ENSE00001964251	41973804	41973958
ENSE00001974994	41972763	41972998
ENSE00001978480	41981305	41981456

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 75.46.

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.46	gold quality
skin of leg	UBERON:0001511	72.48	gold quality
skin of abdomen	UBERON:0001416	70.55	gold quality
zone of skin	UBERON:0000014	68.36	gold quality
buccal mucosa cell	CL:0002336	65.16	gold quality
lower lobe of lung	UBERON:0008949	58.30	silver quality
minor salivary gland	UBERON:0001830	57.24	gold quality
lower esophagus muscularis layer	UBERON:0035833	56.05	gold quality
esophagus mucosa	UBERON:0002469	54.42	gold quality
esophagus	UBERON:0001043	54.38	gold quality
endothelial cell	CL:0000115	54.23	gold quality
tibial nerve	UBERON:0001323	53.68	gold quality
left ovary	UBERON:0002119	53.62	gold quality
pons	UBERON:0000988	52.48	gold quality
uterine cervix	UBERON:0000002	51.99	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	51.63	gold quality
lower esophagus mucosa	UBERON:0035834	51.04	gold quality
mouth mucosa	UBERON:0003729	50.46	gold quality
gall bladder	UBERON:0002110	50.11	gold quality
saliva-secreting gland	UBERON:0001044	49.95	gold quality
upper lobe of lung	UBERON:0008948	49.12	silver quality
ectocervix	UBERON:0012249	48.71	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.33	gold quality
anatomical system	UBERON:0000467	48.11	gold quality
vagina	UBERON:0000996	47.89	gold quality
multicellular organism	UBERON:0000468	47.68	gold quality
material anatomical entity	UBERON:0000465	47.65	gold quality
islet of Langerhans	UBERON:0000006	46.87	silver quality
muscle of leg	UBERON:0001383	46.03	gold quality
tonsil	UBERON:0002372	45.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.