PLBD1-AS1

Summary

PLBD1-AS1 (PLBD1 antisense RNA 1, HGNC:51143) is a long non-coding RNA gene on chromosome 12p13.1-p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51143
Approved symbol	PLBD1-AS1
Name	PLBD1 antisense RNA 1
Location	12p13.1-p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256751
Ensembl biotype	lncRNA
Entrez	101928290
RNAcentral	URS000075C467 — lncRNA, 586 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000542401, ENST00000545424, ENST00000660979, ENST00000746767

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000542401 — 5 exons

Exon	Start	End
ENSE00002238486	14612879	14612926
ENSE00002290205	14619152	14619373
ENSE00002320143	14614522	14614570
ENSE00003874546	14619738	14622721
ENSE00003880131	14567393	14568192

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 80.13.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1893 / max 50.1962, expressed in 505 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
124454	0.9453	424
124453	0.2440	136

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.13	gold quality
monocyte	CL:0000576	79.46	gold quality
leukocyte	CL:0000738	78.94	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.05	gold quality
rectum	UBERON:0001052	76.86	gold quality
esophagus mucosa	UBERON:0002469	74.42	gold quality
blood	UBERON:0000178	74.17	gold quality
heart left ventricle	UBERON:0002084	73.55	gold quality
lower esophagus mucosa	UBERON:0035834	72.95	gold quality
body of pancreas	UBERON:0001150	72.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.66	gold quality
bone marrow cell	CL:0002092	72.40	gold quality
apex of heart	UBERON:0002098	71.93	gold quality
duodenum	UBERON:0002114	71.84	gold quality
skeletal muscle tissue	UBERON:0001134	71.60	gold quality
pancreas	UBERON:0001264	71.33	gold quality
mucosa of transverse colon	UBERON:0004991	71.11	gold quality
heart	UBERON:0000948	70.88	gold quality
stromal cell of endometrium	CL:0002255	70.34	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.05	gold quality
right atrium auricular region	UBERON:0006631	69.81	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
granulocyte	CL:0000094	69.32	gold quality
gall bladder	UBERON:0002110	69.27	gold quality
colonic epithelium	UBERON:0000397	69.26	silver quality
smooth muscle tissue	UBERON:0001135	69.11	gold quality
transverse colon	UBERON:0001157	68.94	gold quality
placenta	UBERON:0001987	68.49	gold quality
islet of Langerhans	UBERON:0000006	68.24	gold quality
bone marrow	UBERON:0002371	68.22	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	6.51
E-ANND-3	no	1.70

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.