PLCB1-IT1

Summary

PLCB1-IT1 (PLCB1 intronic transcript 1, HGNC:41414) is a long non-coding RNA gene on chromosome 20p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41414
Approved symbol	PLCB1-IT1
Name	PLCB1 intronic transcript 1
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225479
Ensembl biotype	lncRNA
Entrez	100874337
RNAcentral	URS000048F109 — lncRNA, 373 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000441231, ENST00000451443

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441231 — 2 exons

Exon	Start	End
ENSE00004264474	8249457	8249742
ENSE00004264475	8248664	8248790

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 93.35.

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.35	gold quality
corpus callosum	UBERON:0002336	84.34	gold quality
tonsil	UBERON:0002372	80.48	gold quality
primary visual cortex	UBERON:0002436	75.35	gold quality
skeletal muscle tissue	UBERON:0001134	74.09	gold quality
urinary bladder	UBERON:0001255	72.89	gold quality
bone marrow cell	CL:0002092	72.80	gold quality
colonic epithelium	UBERON:0000397	72.38	gold quality
kidney	UBERON:0002113	71.65	gold quality
stomach	UBERON:0000945	71.10	gold quality
blood	UBERON:0000178	70.94	gold quality
calcaneal tendon	UBERON:0003701	70.25	gold quality
adrenal tissue	UBERON:0018303	70.20	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.30	gold quality
left testis	UBERON:0004533	67.16	gold quality
prefrontal cortex	UBERON:0000451	66.99	gold quality
right testis	UBERON:0004534	66.80	gold quality
testis	UBERON:0000473	66.70	gold quality
bone marrow	UBERON:0002371	66.36	gold quality
liver	UBERON:0002107	66.10	gold quality
adult mammalian kidney	UBERON:0000082	62.65	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.34	gold quality
lung	UBERON:0002048	61.61	gold quality
monocyte	CL:0000576	60.99	gold quality
adrenal gland	UBERON:0002369	59.27	gold quality
intestine	UBERON:0000160	57.35	gold quality
heart	UBERON:0000948	57.22	gold quality
multicellular organism	UBERON:0000468	56.50	gold quality
colon	UBERON:0001155	56.40	gold quality
thoracic mammary gland	UBERON:0005200	56.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.