PLCB2-AS1

Summary

PLCB2-AS1 (PLCB2 antisense RNA 1, HGNC:43662) is a long non-coding RNA gene on chromosome 15q15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43662
Approved symbol	PLCB2-AS1
Name	PLCB2 antisense RNA 1
Location	15q15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259307
Ensembl biotype	lncRNA
Entrez	100874186
RNAcentral	URS00000FFA89 — lncRNA, 568 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000559520

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559520 — 2 exons

Exon	Start	End
ENSE00002539058	40301609	40301820
ENSE00002542871	40300670	40301025

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 78.15.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	78.15	gold quality
bone marrow cell	CL:0002092	75.22	gold quality
sural nerve	UBERON:0015488	73.92	silver quality
granulocyte	CL:0000094	69.48	gold quality
bone marrow	UBERON:0002371	68.81	gold quality
blood	UBERON:0000178	66.92	gold quality
vermiform appendix	UBERON:0001154	64.42	gold quality
lymph node	UBERON:0000029	64.25	gold quality
leukocyte	CL:0000738	60.28	gold quality
islet of Langerhans	UBERON:0000006	59.81	gold quality
monocyte	CL:0000576	59.61	gold quality
skeletal muscle tissue	UBERON:0001134	59.47	gold quality
muscle tissue	UBERON:0002385	59.35	gold quality
spleen	UBERON:0002106	58.60	gold quality
smooth muscle tissue	UBERON:0001135	57.05	gold quality
tonsil	UBERON:0002372	56.58	gold quality
liver	UBERON:0002107	56.37	gold quality
placenta	UBERON:0001987	54.53	gold quality
prefrontal cortex	UBERON:0000451	53.62	gold quality
duodenum	UBERON:0002114	53.61	gold quality
rectum	UBERON:0001052	53.17	gold quality
right uterine tube	UBERON:0001302	53.07	gold quality
right lobe of liver	UBERON:0001114	51.99	gold quality
gall bladder	UBERON:0002110	51.85	gold quality
right lung	UBERON:0002167	51.48	gold quality
cortex of kidney	UBERON:0001225	51.13	gold quality
adenohypophysis	UBERON:0002196	50.95	gold quality
metanephros cortex	UBERON:0010533	50.03	gold quality
multicellular organism	UBERON:0000468	50.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.