PLCE1-AS1

Summary

PLCE1-AS1 (PLCE1 antisense RNA 1, HGNC:45193) is a long non-coding RNA gene on chromosome 10q23.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45193
Approved symbol	PLCE1-AS1
Name	PLCE1 antisense RNA 1
Location	10q23.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268894
Ensembl biotype	lncRNA
Entrez	100128054
RNAcentral	URS000075B3D1 — lncRNA, 1408 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000425267, ENST00000440198, ENST00000596633, ENST00000611247, ENST00000747724

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425267 — 4 exons

Exon	Start	End
ENSE00001658942	94280594	94280629
ENSE00001754434	94283387	94283486
ENSE00004089849	94278280	94280331
ENSE00004089852	94286841	94287071

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 84.67.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5076 / max 58.0641, expressed in 152 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
110727	0.2536	107
110725	0.1603	64
110726	0.0506	24
110724	0.0431	16

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.67	gold quality
placenta	UBERON:0001987	73.86	gold quality
ventricular zone	UBERON:0003053	71.89	gold quality
sural nerve	UBERON:0015488	71.26	gold quality
ganglionic eminence	UBERON:0004023	70.38	gold quality
colonic epithelium	UBERON:0000397	68.92	silver quality
popliteal artery	UBERON:0002250	67.59	gold quality
tibial artery	UBERON:0007610	67.59	gold quality
stromal cell of endometrium	CL:0002255	67.31	gold quality
skeletal muscle tissue	UBERON:0001134	63.80	silver quality
calcaneal tendon	UBERON:0003701	63.22	gold quality
cortical plate	UBERON:0005343	62.53	gold quality
liver	UBERON:0002107	61.01	silver quality
right uterine tube	UBERON:0001302	59.70	gold quality
lower esophagus	UBERON:0013473	57.69	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.67	gold quality
right lobe of thyroid gland	UBERON:0001119	57.57	gold quality
tibial nerve	UBERON:0001323	57.29	gold quality
mucosa of stomach	UBERON:0001199	56.39	gold quality
tonsil	UBERON:0002372	56.01	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	55.60	gold quality
ascending aorta	UBERON:0001496	55.22	gold quality
endometrium	UBERON:0001295	55.20	gold quality
left lobe of thyroid gland	UBERON:0001120	55.11	gold quality
thyroid gland	UBERON:0002046	55.10	gold quality
urinary bladder	UBERON:0001255	55.07	gold quality
left coronary artery	UBERON:0001626	54.80	gold quality
thoracic aorta	UBERON:0001515	54.77	gold quality
right atrium auricular region	UBERON:0006631	54.31	gold quality
prefrontal cortex	UBERON:0000451	54.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.