PLCL2-AS1

Summary

PLCL2-AS1 (PLCL2 antisense RNA 1, HGNC:40449) is a long non-coding RNA gene on chromosome 3p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40449
Approved symbol	PLCL2-AS1
Name	PLCL2 antisense RNA 1
Location	3p24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226441
Ensembl biotype	lncRNA
Entrez	100874003
RNAcentral	URS00025E35AE — lncRNA, 356 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000414844, ENST00000832884

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414844 — 2 exons

Exon	Start	End
ENSE00001633125	17044054	17044192
ENSE00001654451	17042742	17042913

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 91.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0967 / max 158.7129, expressed in 5 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41357	0.0478	3
41355	0.0343	4
41356	0.0146	3

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.82	gold quality
sural nerve	UBERON:0015488	78.64	gold quality
hindlimb stylopod muscle	UBERON:0004252	75.80	gold quality
bone marrow cell	CL:0002092	73.70	gold quality
colonic epithelium	UBERON:0000397	73.67	gold quality
skeletal muscle tissue	UBERON:0001134	72.29	gold quality
calcaneal tendon	UBERON:0003701	71.97	gold quality
bone marrow	UBERON:0002371	69.40	gold quality
primary visual cortex	UBERON:0002436	66.18	gold quality
blood	UBERON:0000178	66.14	gold quality
adrenal tissue	UBERON:0018303	64.91	gold quality
prefrontal cortex	UBERON:0000451	64.30	gold quality
monocyte	CL:0000576	62.45	gold quality
corpus callosum	UBERON:0002336	61.79	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.42	gold quality
kidney	UBERON:0002113	60.09	gold quality
tonsil	UBERON:0002372	59.90	silver quality
islet of Langerhans	UBERON:0000006	59.78	gold quality
muscle of leg	UBERON:0001383	59.65	gold quality
adult mammalian kidney	UBERON:0000082	58.47	gold quality
heart left ventricle	UBERON:0002084	58.34	gold quality
placenta	UBERON:0001987	58.29	gold quality
myometrium	UBERON:0001296	58.26	gold quality
gastrocnemius	UBERON:0001388	58.16	gold quality
liver	UBERON:0002107	57.94	gold quality
heart	UBERON:0000948	57.88	gold quality
uterine cervix	UBERON:0000002	56.69	gold quality
right atrium auricular region	UBERON:0006631	56.57	gold quality
stomach	UBERON:0000945	55.72	gold quality
adrenal gland	UBERON:0002369	55.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.