PLPPR5-AS1

Summary

PLPPR5-AS1 (PLPPR5 antisense RNA 1, HGNC:55720) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55720
Approved symbol	PLPPR5-AS1
Name	PLPPR5 antisense RNA 1
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232825
Ensembl biotype	lncRNA
Entrez	100129620
RNAcentral	URS00000EDD2D — lncRNA, 2544 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000425113, ENST00000647692, ENST00000658279, ENST00000660510, ENST00000662973, ENST00000785584, ENST00000785585, ENST00000785586

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425113 — 3 exons

Exon	Start	End
ENSE00001609717	99146774	99148852
ENSE00001630722	99144036	99144130
ENSE00001769969	99004276	99004645

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 75.05.

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.05	silver quality
cortical plate	UBERON:0005343	69.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.93	silver quality
ventricular zone	UBERON:0003053	60.58	gold quality
prefrontal cortex	UBERON:0000451	59.69	gold quality
ganglionic eminence	UBERON:0004023	59.08	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.77	gold quality
tendon of biceps brachii	UBERON:0008188	54.41	gold quality
anterior cingulate cortex	UBERON:0009835	53.94	gold quality
neocortex	UBERON:0001950	53.70	gold quality
frontal cortex	UBERON:0001870	53.54	gold quality
nucleus accumbens	UBERON:0001882	53.25	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	52.51	gold quality
right frontal lobe	UBERON:0002810	51.33	gold quality
cerebral cortex	UBERON:0000956	50.87	gold quality
right hemisphere of cerebellum	UBERON:0014890	49.56	gold quality
hypothalamus	UBERON:0001898	49.50	gold quality
forebrain	UBERON:0001890	49.25	gold quality
testis	UBERON:0000473	49.10	gold quality
brain	UBERON:0000955	48.65	gold quality
cerebellar hemisphere	UBERON:0002245	48.58	gold quality
monocyte	CL:0000576	48.37	silver quality
caudate nucleus	UBERON:0001873	48.20	gold quality
cerebellar cortex	UBERON:0002129	47.93	gold quality
amygdala	UBERON:0001876	47.68	gold quality
primary visual cortex	UBERON:0002436	47.44	gold quality
putamen	UBERON:0001874	47.11	gold quality
Ammon’s horn	UBERON:0001954	46.25	gold quality
islet of Langerhans	UBERON:0000006	45.99	silver quality
occipital lobe	UBERON:0002021	45.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.