PLS1-AS1

Summary

PLS1-AS1 (PLS1 antisense RNA 1, HGNC:40451) is a long non-coding RNA gene on chromosome 3q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40451
Approved symbol	PLS1-AS1
Name	PLS1 antisense RNA 1
Location	3q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239641
Ensembl biotype	lncRNA
Entrez	105374136
RNAcentral	URS0002A3847E — lncRNA, 524 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000485338

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000485338 — 2 exons

Exon	Start	End
ENSE00004068257	142654697	142654941
ENSE00004068258	142656558	142656836

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 79.04.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	79.04	gold quality
bone marrow	UBERON:0002371	63.87	gold quality
monocyte	CL:0000576	60.88	gold quality
kidney	UBERON:0002113	58.89	gold quality
islet of Langerhans	UBERON:0000006	58.17	gold quality
adult mammalian kidney	UBERON:0000082	58.03	gold quality
mucosa of transverse colon	UBERON:0004991	57.82	gold quality
blood	UBERON:0000178	57.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.82	gold quality
cortex of kidney	UBERON:0001225	56.23	gold quality
endometrium	UBERON:0001295	55.54	gold quality
primary visual cortex	UBERON:0002436	55.01	gold quality
right testis	UBERON:0004534	54.79	gold quality
testis	UBERON:0000473	53.94	gold quality
left testis	UBERON:0004533	53.82	gold quality
body of pancreas	UBERON:0001150	53.21	gold quality
rectum	UBERON:0001052	53.12	gold quality
amygdala	UBERON:0001876	53.02	gold quality
liver	UBERON:0002107	52.75	gold quality
small intestine	UBERON:0002108	52.74	gold quality
tibial artery	UBERON:0007610	52.56	gold quality
intestine	UBERON:0000160	52.50	gold quality
small intestine Peyer’s patch	UBERON:0003454	51.90	gold quality
colon	UBERON:0001155	51.88	gold quality
stomach	UBERON:0000945	51.56	gold quality
fundus of stomach	UBERON:0001160	50.79	gold quality
multicellular organism	UBERON:0000468	49.85	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	49.70	gold quality
gastrocnemius	UBERON:0001388	49.65	silver quality
transverse colon	UBERON:0001157	49.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.