PLUT

Summary

PLUT (PDX1 associated lncRNA, upregulator of transcription, HGNC:43698) is a long non-coding RNA gene on chromosome 13q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43698
Approved symbol	PLUT
Name	PDX1 associated lncRNA, upregulator of transcription
Location	13q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	PLUTO, HI-LNC71
Ensembl gene	ENSG00000247381
Ensembl biotype	lncRNA
OMIM	621241
Entrez	100861550
RNAcentral	URS0000ABD8D4 — lncRNA, 2254 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000499662

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499662 — 5 exons

Exon	Start	End
ENSE00001967059	27848008	27848536
ENSE00001972279	27834021	27834150
ENSE00003812294	27917150	27917298
ENSE00003812873	27822755	27823372
ENSE00003813606	27819376	27820467

Expression profiles

Bgee: expression breadth broad, 15 present calls, max score 79.69.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0564 / max 8.4987, expressed in 32 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
136502	0.0564	32

Top tissues by expression

15 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
islet of Langerhans	UBERON:0000006	79.69	gold quality
pancreas	UBERON:0001264	63.38	gold quality
duodenum	UBERON:0002114	53.65	gold quality
small intestine	UBERON:0002108	50.05	gold quality
gall bladder	UBERON:0002110	48.00	gold quality
intestine	UBERON:0000160	47.55	gold quality
stomach	UBERON:0000945	45.00	gold quality
transverse colon	UBERON:0001157	44.28	gold quality
colon	UBERON:0001155	44.25	silver quality
body of pancreas	UBERON:0001150	44.08	silver quality
body of stomach	UBERON:0001161	43.43	silver quality
small intestine Peyer’s patch	UBERON:0003454	38.87	silver quality
right testis	UBERON:0004534	33.73	silver quality
testis	UBERON:0000473	32.52	silver quality
left testis	UBERON:0004533	32.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.