PLXNA4-AS1

Summary

PLXNA4-AS1 (PLXNA4 antisense RNA 1, HGNC:40453) is a long non-coding RNA gene on chromosome 7q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40453
Approved symbol	PLXNA4-AS1
Name	PLXNA4 antisense RNA 1
Location	7q32.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223436
Ensembl biotype	lncRNA
Entrez	139355213
RNAcentral	URS00004F46DA — lncRNA, 526 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000455442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455442 — 3 exons

Exon	Start	End
ENSE00001630566	132352334	132352381
ENSE00001664924	132365924	132366067
ENSE00001680546	132367643	132367976

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 68.23.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	68.23	gold quality
ganglionic eminence	UBERON:0004023	65.85	gold quality
placenta	UBERON:0001987	62.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.48	gold quality
islet of Langerhans	UBERON:0000006	60.05	gold quality
descending thoracic aorta	UBERON:0002345	59.92	gold quality
skeletal muscle tissue	UBERON:0001134	59.56	silver quality
calcaneal tendon	UBERON:0003701	59.15	gold quality
right coronary artery	UBERON:0001625	59.10	gold quality
lymph node	UBERON:0000029	58.85	gold quality
thoracic aorta	UBERON:0001515	58.55	gold quality
ascending aorta	UBERON:0001496	58.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.25	gold quality
prefrontal cortex	UBERON:0000451	53.78	gold quality
myometrium	UBERON:0001296	53.78	gold quality
blood	UBERON:0000178	52.74	gold quality
monocyte	CL:0000576	52.62	gold quality
kidney	UBERON:0002113	52.07	gold quality
primary visual cortex	UBERON:0002436	50.77	gold quality
right lobe of liver	UBERON:0001114	50.21	gold quality
popliteal artery	UBERON:0002250	50.12	gold quality
tibial artery	UBERON:0007610	50.04	gold quality
corpus callosum	UBERON:0002336	49.56	gold quality
adult mammalian kidney	UBERON:0000082	49.50	gold quality
mucosa of stomach	UBERON:0001199	49.14	gold quality
adrenal tissue	UBERON:0018303	48.86	gold quality
heart	UBERON:0000948	48.31	gold quality
left coronary artery	UBERON:0001626	47.45	gold quality
tonsil	UBERON:0002372	47.07	gold quality
gastrocnemius	UBERON:0001388	46.20	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.