PLXNA4-AS2

Summary

PLXNA4-AS2 (PLXNA4 antisense RNA 2, HGNC:40452) is a long non-coding RNA gene on chromosome 7q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40452
Approved symbol	PLXNA4-AS2
Name	PLXNA4 antisense RNA 2
Location	7q32.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225144
Ensembl biotype	lncRNA
Entrez	101928807
RNAcentral	URS0000A771C2 — lncRNA, 466 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000445459, ENST00000823054

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445459 — 3 exons

Exon	Start	End
ENSE00001657604	132271113	132271269
ENSE00001678104	132266259	132266365
ENSE00001787778	132264152	132264301

Expression profiles

Bgee: expression breadth broad, 70 present calls, max score 67.35.

Top tissues by expression

70 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
kidney	UBERON:0002113	67.35	gold quality
endometrium	UBERON:0001295	62.04	gold quality
colonic epithelium	UBERON:0000397	61.66	silver quality
myometrium	UBERON:0001296	61.29	gold quality
calcaneal tendon	UBERON:0003701	58.37	gold quality
corpus callosum	UBERON:0002336	57.95	gold quality
monocyte	CL:0000576	57.86	gold quality
superior frontal gyrus	UBERON:0002661	57.14	gold quality
adrenal tissue	UBERON:0018303	55.78	gold quality
heart	UBERON:0000948	54.22	gold quality
blood	UBERON:0000178	54.05	gold quality
primary visual cortex	UBERON:0002436	53.92	gold quality
left testis	UBERON:0004533	52.24	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	52.20	gold quality
gastrocnemius	UBERON:0001388	52.14	gold quality
stomach	UBERON:0000945	50.90	gold quality
testis	UBERON:0000473	50.60	gold quality
tibial artery	UBERON:0007610	49.84	gold quality
popliteal artery	UBERON:0002250	49.62	gold quality
right testis	UBERON:0004534	48.96	gold quality
lung	UBERON:0002048	48.74	gold quality
body of uterus	UBERON:0009853	48.25	gold quality
prefrontal cortex	UBERON:0000451	48.08	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	47.56	gold quality
multicellular organism	UBERON:0000468	47.35	gold quality
subcutaneous adipose tissue	UBERON:0002190	47.29	gold quality
thoracic mammary gland	UBERON:0005200	47.23	gold quality
heart left ventricle	UBERON:0002084	47.01	gold quality
ascending aorta	UBERON:0001496	46.73	gold quality
substantia nigra	UBERON:0002038	46.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.