PLXNB3-AS1

Summary

PLXNB3-AS1 (PLXNB3 antisense RNA 1, HGNC:40454) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40454
Approved symbol	PLXNB3-AS1
Name	PLXNB3 antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232725
Ensembl biotype	lncRNA
Entrez	102723591
RNAcentral	URS0002A7053D — lncRNA, 1543 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000416854, ENST00000434284, ENST00000815145, ENST00000815146, ENST00000815147, ENST00000815148, ENST00000815149, ENST00000815150, ENST00000815151, ENST00000815152, ENST00000815153

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416854 — 3 exons

Exon	Start	End
ENSE00001627836	153766383	153766478
ENSE00001653148	153760491	153760613
ENSE00001703366	153763793	153763817

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 93.55.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	93.55	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.83	gold quality
muscle layer of sigmoid colon	UBERON:0035805	86.64	gold quality
tibial nerve	UBERON:0001323	83.93	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	82.97	gold quality
descending thoracic aorta	UBERON:0002345	82.62	gold quality
lower esophagus muscularis layer	UBERON:0035833	82.17	gold quality
lower esophagus	UBERON:0013473	82.14	gold quality
mucosa of stomach	UBERON:0001199	82.07	gold quality
body of uterus	UBERON:0009853	81.98	gold quality
bone marrow cell	CL:0002092	81.72	gold quality
colonic epithelium	UBERON:0000397	81.68	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	81.64	gold quality
thoracic aorta	UBERON:0001515	80.79	gold quality
ascending aorta	UBERON:0001496	80.60	gold quality
left adrenal gland cortex	UBERON:0035825	80.34	gold quality
left uterine tube	UBERON:0001303	80.18	gold quality
stromal cell of endometrium	CL:0002255	79.95	gold quality
myometrium	UBERON:0001296	79.91	gold quality
left adrenal gland	UBERON:0001234	79.21	gold quality
right adrenal gland	UBERON:0001233	78.96	gold quality
right adrenal gland cortex	UBERON:0035827	78.92	gold quality
colon	UBERON:0001155	77.93	gold quality
substantia nigra	UBERON:0002038	77.71	gold quality
adrenal gland	UBERON:0002369	77.21	gold quality
Ammon’s horn	UBERON:0001954	76.91	gold quality
subcutaneous adipose tissue	UBERON:0002190	76.15	gold quality
fundus of stomach	UBERON:0001160	76.11	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.64	silver quality
right frontal lobe	UBERON:0002810	75.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.