PLXNC1-AS1

Summary

PLXNC1-AS1 (PLXNC1 antisense RNA 1, HGNC:58451) is a long non-coding RNA gene on chromosome 12q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58451
Approved symbol	PLXNC1-AS1
Name	PLXNC1 antisense RNA 1
Location	12q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258035
Ensembl biotype	lncRNA
Entrez	124902988

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000550759, ENST00000551029, ENST00000659763, ENST00000669622

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000550759 — 2 exons

Exon	Start	End
ENSE00002345848	94185942	94186044
ENSE00002386131	94168009	94168351

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 77.85.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	77.85	gold quality
bone marrow	UBERON:0002371	71.87	gold quality
blood	UBERON:0000178	70.18	gold quality
pituitary gland	UBERON:0000007	65.88	gold quality
ventricular zone	UBERON:0003053	65.01	gold quality
adenohypophysis	UBERON:0002196	63.41	gold quality
cortical plate	UBERON:0005343	61.13	silver quality
prefrontal cortex	UBERON:0000451	60.51	gold quality
ganglionic eminence	UBERON:0004023	60.02	gold quality
muscle tissue	UBERON:0002385	59.66	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	59.20	gold quality
nucleus accumbens	UBERON:0001882	59.13	gold quality
frontal cortex	UBERON:0001870	58.37	gold quality
monocyte	CL:0000576	57.12	gold quality
granulocyte	CL:0000094	57.10	gold quality
primary visual cortex	UBERON:0002436	56.93	gold quality
superior frontal gyrus	UBERON:0002661	56.69	gold quality
islet of Langerhans	UBERON:0000006	55.95	gold quality
cerebral cortex	UBERON:0000956	55.95	gold quality
brain	UBERON:0000955	55.39	gold quality
right frontal lobe	UBERON:0002810	55.33	gold quality
tonsil	UBERON:0002372	55.16	silver quality
hypothalamus	UBERON:0001898	55.13	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.83	gold quality
multicellular organism	UBERON:0000468	54.62	gold quality
sural nerve	UBERON:0015488	54.39	silver quality
caudate nucleus	UBERON:0001873	54.21	gold quality
Ammon’s horn	UBERON:0001954	53.84	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.57	gold quality
putamen	UBERON:0001874	53.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.