PMM2-AS1

Summary

PMM2-AS1 (PMM2 antisense RNA 1, HGNC:58482) is a long non-coding RNA gene on chromosome 16p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58482
Approved symbol	PMM2-AS1
Name	PMM2 antisense RNA 1
Location	16p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260350
Ensembl biotype	lncRNA
Entrez	141974276

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000567942

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000567942 — 2 exons

Exon	Start	End
ENSE00002578535	8848636	8848724
ENSE00002601601	8847650	8847990

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 73.36.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	73.36	gold quality
cortical plate	UBERON:0005343	72.63	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.32	gold quality
ventricular zone	UBERON:0003053	70.21	gold quality
lower esophagus mucosa	UBERON:0035834	70.07	gold quality
stromal cell of endometrium	CL:0002255	69.72	gold quality
apex of heart	UBERON:0002098	69.59	gold quality
mucosa of transverse colon	UBERON:0004991	69.33	gold quality
sural nerve	UBERON:0015488	69.11	silver quality
bone marrow cell	CL:0002092	66.82	silver quality
granulocyte	CL:0000094	65.39	gold quality
right lobe of liver	UBERON:0001114	65.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.29	gold quality
liver	UBERON:0002107	64.04	gold quality
vermiform appendix	UBERON:0001154	63.43	gold quality
skeletal muscle tissue	UBERON:0001134	63.27	gold quality
gall bladder	UBERON:0002110	62.40	gold quality
bone marrow	UBERON:0002371	62.08	gold quality
primary visual cortex	UBERON:0002436	61.53	gold quality
nucleus accumbens	UBERON:0001882	61.01	gold quality
omental fat pad	UBERON:0010414	60.25	gold quality
cortex of kidney	UBERON:0001225	60.24	gold quality
body of pancreas	UBERON:0001150	60.06	gold quality
pancreas	UBERON:0001264	59.99	gold quality
adipose tissue	UBERON:0001013	59.80	gold quality
duodenum	UBERON:0002114	59.79	gold quality
endometrium	UBERON:0001295	59.72	gold quality
esophagus mucosa	UBERON:0002469	59.55	gold quality
blood	UBERON:0000178	59.47	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.