PNN-AS1

Summary

PNN-AS1 (PNN antisense RNA 1, HGNC:55974) is a long non-coding RNA gene on chromosome 14q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55974
Approved symbol	PNN-AS1
Name	PNN antisense RNA 1
Location	14q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259083
Ensembl biotype	lncRNA
Entrez	123466206
RNAcentral	URS0002347EB3 — lncRNA, 540 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000556537

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556537 — 2 exons

Exon	Start	End
ENSE00004101894	39175779	39175880
ENSE00004101895	39174875	39175312

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 83.25.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.25	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.31	silver quality
bone marrow cell	CL:0002092	69.53	silver quality
ventricular zone	UBERON:0003053	67.17	gold quality
ganglionic eminence	UBERON:0004023	65.82	gold quality
bone marrow	UBERON:0002371	65.43	gold quality
lymph node	UBERON:0000029	64.39	gold quality
monocyte	CL:0000576	62.23	gold quality
duodenum	UBERON:0002114	61.54	gold quality
testis	UBERON:0000473	60.25	gold quality
left testis	UBERON:0004533	60.11	gold quality
right lobe of liver	UBERON:0001114	59.68	gold quality
liver	UBERON:0002107	59.57	gold quality
right testis	UBERON:0004534	59.49	gold quality
vermiform appendix	UBERON:0001154	59.46	gold quality
gall bladder	UBERON:0002110	59.06	gold quality
tonsil	UBERON:0002372	58.35	gold quality
blood	UBERON:0000178	58.24	gold quality
granulocyte	CL:0000094	56.17	gold quality
islet of Langerhans	UBERON:0000006	56.04	gold quality
vagina	UBERON:0000996	55.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.23	gold quality
mucosa of transverse colon	UBERON:0004991	54.92	gold quality
uterine cervix	UBERON:0000002	54.83	gold quality
endocervix	UBERON:0000458	54.71	gold quality
prefrontal cortex	UBERON:0000451	54.16	gold quality
stromal cell of endometrium	CL:0002255	54.00	silver quality
ectocervix	UBERON:0012249	53.31	gold quality
esophagus mucosa	UBERON:0002469	53.28	gold quality
placenta	UBERON:0001987	52.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.