POC1B-AS1

Summary

POC1B-AS1 (POC1B antisense RNA 1, HGNC:52949) is a long non-coding RNA gene on chromosome 12q21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52949
Approved symbol	POC1B-AS1
Name	POC1B antisense RNA 1
Location	12q21.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-734K2.4
Ensembl gene	ENSG00000270344
Ensembl biotype	lncRNA
Entrez	109729146
RNAcentral	URS0000BC4596 — lncRNA, 1662 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000605233, ENST00000655646, ENST00000701842, ENST00000716324, ENST00000716325, ENST00000716326, ENST00000716327, ENST00000716328, ENST00000716329, ENST00000716330, ENST00000716331, ENST00000716332, ENST00000716333, ENST00000716334, ENST00000716335, ENST00000716336, ENST00000830688, ENST00000830689, ENST00000830690, ENST00000830691, ENST00000830692, ENST00000830693, ENST00000830694, ENST00000830695, ENST00000830696, ENST00000830697, ENST00000830698

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000605233 — 3 exons

Exon	Start	End
ENSE00003869849	89525577	89525796
ENSE00004245417	89524545	89524633
ENSE00004245427	89540108	89548005

Expression profiles

Bgee: expression breadth ubiquitous, 241 present calls, max score 92.13.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6192 / max 12.5491, expressed in 357 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
127252	0.3456	206
127253	0.2736	119

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
kidney epithelium	UBERON:0004819	92.13	silver quality
sperm	CL:0000019	91.93	gold quality
left ventricle myocardium	UBERON:0006566	89.84	silver quality
cerebellar vermis	UBERON:0004720	86.18	silver quality
vena cava	UBERON:0004087	85.34	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	84.03	silver quality
body of tongue	UBERON:0011876	82.85	silver quality
cardia of stomach	UBERON:0001162	82.34	silver quality
trachea	UBERON:0003126	81.77	silver quality
pericardium	UBERON:0002407	81.51	gold quality
tongue	UBERON:0001723	81.11	silver quality
inferior vagus X ganglion	UBERON:0005363	81.00	silver quality
epithelial cell of pancreas	CL:0000083	80.99	silver quality
subthalamic nucleus	UBERON:0001906	80.95	silver quality
substantia nigra pars reticulata	UBERON:0001966	80.72	silver quality
lateral globus pallidus	UBERON:0002476	80.68	silver quality
dorsal plus ventral thalamus	UBERON:0001897	80.48	silver quality
ventral tegmental area	UBERON:0002691	80.34	silver quality
superior surface of tongue	UBERON:0007371	80.27	silver quality
layer of synovial tissue	UBERON:0007616	80.05	silver quality
lateral nuclear group of thalamus	UBERON:0002736	79.94	silver quality
medulla oblongata	UBERON:0001896	79.85	silver quality
pharyngeal mucosa	UBERON:0000355	79.72	silver quality
saphenous vein	UBERON:0007318	79.72	silver quality
superior vestibular nucleus	UBERON:0007227	79.60	gold quality
pylorus	UBERON:0001166	79.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.41	gold quality
tendon of biceps brachii	UBERON:0008188	79.36	gold quality
pons	UBERON:0000988	79.22	gold quality
substantia nigra pars compacta	UBERON:0001965	79.19	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	5.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.