POLG-DT

Summary

POLG-DT (POLG divergent transcript, HGNC:55363) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55363
Approved symbol	POLG-DT
Name	POLG divergent transcript
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261441
Ensembl biotype	lncRNA
Entrez	119545629
RNAcentral	URS00026A1F3B — lncRNA, 1343 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000562356, ENST00000569473, ENST00000837147, ENST00000837148, ENST00000837149, ENST00000837150, ENST00000837151, ENST00000837152

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562356 — 2 exons

Exon	Start	End
ENSE00002586345	89335649	89336161
ENSE00002592636	89335271	89335369

Expression profiles

Bgee: expression breadth ubiquitous, 140 present calls, max score 84.20.

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.20	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.04	gold quality
sural nerve	UBERON:0015488	76.76	gold quality
left testis	UBERON:0004533	74.93	gold quality
right testis	UBERON:0004534	73.96	gold quality
testis	UBERON:0000473	72.80	gold quality
sperm	CL:0000019	71.77	silver quality
bone marrow cell	CL:0002092	66.94	silver quality
tibialis anterior	UBERON:0001385	64.98	silver quality
pancreatic ductal cell	CL:0002079	64.51	silver quality
granulocyte	CL:0000094	63.00	gold quality
adult organism	UBERON:0007023	62.80	gold quality
cortical plate	UBERON:0005343	60.77	gold quality
adrenal tissue	UBERON:0018303	58.82	gold quality
deltoid	UBERON:0001476	58.15	gold quality
myocardium	UBERON:0002349	57.32	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.02	gold quality
epithelial cell of pancreas	CL:0000083	55.20	gold quality
parotid gland	UBERON:0001831	55.09	gold quality
calcaneal tendon	UBERON:0003701	54.89	silver quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
islet of Langerhans	UBERON:0000006	54.05	gold quality
nasal cavity epithelium	UBERON:0005384	54.02	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
prefrontal cortex	UBERON:0000451	53.67	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
biceps brachii	UBERON:0001507	52.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.93	gold quality
quadriceps femoris	UBERON:0001377	52.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.