POLR2F-AS1

Summary

POLR2F-AS1 (POLR2F antisense RNA 1, HGNC:40461) is a long non-coding RNA gene on chromosome 22q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40461
Approved symbol	POLR2F-AS1
Name	POLR2F antisense RNA 1
Location	22q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000222044
Ensembl biotype	lncRNA
Entrez	140577508

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000410099

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000410099 — 2 exons

Exon	Start	End
ENSE00001577387	38034165	38034228
ENSE00001582541	38032165	38033155

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 69.54.

Top tissues by expression

213 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	69.54	gold quality
spinal cord	UBERON:0002240	66.89	gold quality
tibial nerve	UBERON:0001323	66.25	gold quality
parotid gland	UBERON:0001831	65.18	gold quality
sural nerve	UBERON:0015488	63.26	gold quality
substantia nigra	UBERON:0002038	60.59	gold quality
cortical plate	UBERON:0005343	60.58	gold quality
ventricular zone	UBERON:0003053	60.38	gold quality
tonsil	UBERON:0002372	60.09	silver quality
corpus callosum	UBERON:0002336	60.04	gold quality
mucosa of sigmoid colon	UBERON:0004993	60.00	gold quality
biceps brachii	UBERON:0001507	59.89	gold quality
vena cava	UBERON:0004087	59.62	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.52	gold quality
colonic mucosa	UBERON:0000317	59.13	gold quality
prefrontal cortex	UBERON:0000451	58.96	gold quality
amygdala	UBERON:0001876	58.34	gold quality
metanephros	UBERON:0000081	58.21	gold quality
midbrain	UBERON:0001891	58.08	gold quality
ganglionic eminence	UBERON:0004023	57.58	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.42	gold quality
putamen	UBERON:0001874	57.29	gold quality
gingival epithelium	UBERON:0001949	57.10	gold quality
gingiva	UBERON:0001828	56.46	gold quality
caudate nucleus	UBERON:0001873	56.45	gold quality
right frontal lobe	UBERON:0002810	56.06	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	55.97	gold quality
cerebellar cortex	UBERON:0002129	55.92	gold quality
myocardium	UBERON:0002349	55.88	gold quality
cerebellar hemisphere	UBERON:0002245	55.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.