POPDC1-AS1

Summary

POPDC1-AS1 (POPDC1 antisense RNA 1, HGNC:21223) is a long non-coding RNA gene on chromosome 6q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:21223
Approved symbol	POPDC1-AS1
Name	POPDC1 antisense RNA 1
Location	6q21
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA99L11.2
Ensembl gene	ENSG00000203808
Ensembl biotype	lncRNA
Entrez	154442
RNAcentral	URS000075BC9B — lncRNA, 1725 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 84 — 84 lncRNA

ENST00000369120, ENST00000369122, ENST00000580511, ENST00000580854, ENST00000648833, ENST00000653051, ENST00000653219, ENST00000654622, ENST00000655437, ENST00000656875, ENST00000661925, ENST00000662876, ENST00000663357, ENST00000664072, ENST00000666385, ENST00000685326, ENST00000686502, ENST00000687937, ENST00000689513, ENST00000690010, ENST00000828902, ENST00000828903, ENST00000828904, ENST00000828905, ENST00000828906, ENST00000828907, ENST00000828908, ENST00000828909, ENST00000828910, ENST00000828911, ENST00000828912, ENST00000828913, ENST00000828914, ENST00000828915, ENST00000828916, ENST00000828917, ENST00000828918, ENST00000828919, ENST00000828920, ENST00000828921, ENST00000828922, ENST00000828923, ENST00000828924, ENST00000828925, ENST00000828926, ENST00000828927, ENST00000828928, ENST00000828929, ENST00000828930, ENST00000828931, ENST00000828932, ENST00000828933, ENST00000828934, ENST00000828935, ENST00000828936, ENST00000828937, ENST00000828938, ENST00000828939, ENST00000828940, ENST00000828941, ENST00000828942, ENST00000828943, ENST00000828944, ENST00000828945, ENST00000828946, ENST00000828947, ENST00000828948, ENST00000828949, ENST00000828950, ENST00000828951, ENST00000828952, ENST00000828953, ENST00000828954, ENST00000828955, ENST00000828956, ENST00000828957, ENST00000828958, ENST00000828959, ENST00000828960, ENST00000828961, ENST00000828962, ENST00000828963, ENST00000828964, ENST00000828965

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000369120 — 5 exons

Exon	Start	End
ENSE00001448843	105154394	105154491
ENSE00001448849	105147276	105147380
ENSE00002710689	105137770	105137923
ENSE00004241884	105159018	105160132
ENSE00004241961	105137240	105137332

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 84.54.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5900 / max 17.7636, expressed in 322 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
69057	0.5514	308
69058	0.0278	6
69059	0.0107	4

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
gastrocnemius	UBERON:0001388	84.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.38	gold quality
sperm	CL:0000019	84.13	gold quality
muscle of leg	UBERON:0001383	84.01	gold quality
hindlimb stylopod muscle	UBERON:0004252	82.35	gold quality
left testis	UBERON:0004533	80.81	gold quality
right testis	UBERON:0004534	80.44	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.86	gold quality
testis	UBERON:0000473	79.33	gold quality
colonic epithelium	UBERON:0000397	76.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	76.43	gold quality
tibialis anterior	UBERON:0001385	76.11	silver quality
lower esophagus muscularis layer	UBERON:0035833	75.57	gold quality
lower esophagus	UBERON:0013473	75.52	gold quality
skeletal muscle tissue	UBERON:0001134	74.71	gold quality
popliteal artery	UBERON:0002250	73.65	gold quality
tibial artery	UBERON:0007610	73.62	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	73.39	gold quality
heart left ventricle	UBERON:0002084	73.28	gold quality
biceps brachii	UBERON:0001507	73.26	silver quality
bone marrow cell	CL:0002092	72.99	gold quality
cardiac ventricle	UBERON:0002082	72.50	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.94	gold quality
apex of heart	UBERON:0002098	71.77	gold quality
deltoid	UBERON:0001476	71.63	silver quality
right atrium auricular region	UBERON:0006631	71.58	gold quality
aorta	UBERON:0000947	71.50	gold quality
heart	UBERON:0000948	70.81	gold quality
smooth muscle tissue	UBERON:0001135	70.34	gold quality
sural nerve	UBERON:0015488	70.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.75

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway. (PMID:37347740)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.