POU2F3-AS1

Summary

POU2F3-AS1 (POU2F3 antisense RNA 1, HGNC:58296) is a long non-coding RNA gene on chromosome 11q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58296
Approved symbol	POU2F3-AS1
Name	POU2F3 antisense RNA 1
Location	11q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259541
Ensembl biotype	lncRNA
Entrez	649133
RNAcentral	URS000048D209 — lncRNA, 2128 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000558822, ENST00000560930

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558822 — 8 exons

Exon	Start	End
ENSE00002539978	120253584	120253654
ENSE00002541034	120265866	120265932
ENSE00002541250	120254823	120254975
ENSE00002563999	120256012	120256993
ENSE00002567773	120249759	120250405
ENSE00002569847	120254112	120254174
ENSE00002572363	120261289	120261319
ENSE00002574153	120265327	120265440

Expression profiles

Bgee: expression breadth broad, 49 present calls, max score 93.68.

Top tissues by expression

49 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.19	gold quality
placenta	UBERON:0001987	61.19	gold quality
thoracic mammary gland	UBERON:0005200	61.00	gold quality
uterine cervix	UBERON:0000002	58.78	silver quality
tibial nerve	UBERON:0001323	57.00	gold quality
monocyte	CL:0000576	54.51	gold quality
skin of abdomen	UBERON:0001416	53.40	gold quality
zone of skin	UBERON:0000014	52.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.72	gold quality
skin of leg	UBERON:0001511	51.26	gold quality
blood	UBERON:0000178	50.27	silver quality
prefrontal cortex	UBERON:0000451	49.21	gold quality
subcutaneous adipose tissue	UBERON:0002190	48.80	gold quality
multicellular organism	UBERON:0000468	48.17	gold quality
thyroid gland	UBERON:0002046	46.04	silver quality
ectocervix	UBERON:0012249	45.96	gold quality
right lobe of liver	UBERON:0001114	45.73	silver quality
esophagus	UBERON:0001043	45.67	silver quality
stomach	UBERON:0000945	45.65	silver quality
caudate nucleus	UBERON:0001873	44.32	silver quality
vagina	UBERON:0000996	44.27	gold quality
heart left ventricle	UBERON:0002084	43.60	gold quality
left lobe of thyroid gland	UBERON:0001120	43.14	gold quality
gastrocnemius	UBERON:0001388	43.11	silver quality
lung	UBERON:0002048	42.61	silver quality
esophagus mucosa	UBERON:0002469	42.29	silver quality
minor salivary gland	UBERON:0001830	42.19	silver quality
colon	UBERON:0001155	41.92	silver quality
right atrium auricular region	UBERON:0006631	41.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.