PPARGC1A-AS1

Summary

PPARGC1A-AS1 (PPARGC1A antisense RNA 1, HGNC:40462) is a long non-coding RNA gene on chromosome 4p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40462
Approved symbol	PPARGC1A-AS1
Name	PPARGC1A antisense RNA 1
Location	4p15.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC092834.1
Ensembl gene	ENSG00000249453
Ensembl biotype	lncRNA
Entrez	105374527
RNAcentral	URS0000433E1F — lncRNA, 442 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000506514

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506514 — 3 exons

Exon	Start	End
ENSE00002037866	23782249	23782560
ENSE00002061259	23782103	23782140
ENSE00002084500	23779590	23779681

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 94.04.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
rectum	UBERON:0001052	94.04	gold quality
duodenum	UBERON:0002114	88.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.58	gold quality
transverse colon	UBERON:0001157	78.99	gold quality
mucosa of transverse colon	UBERON:0004991	78.76	gold quality
small intestine	UBERON:0002108	77.91	gold quality
small intestine Peyer’s patch	UBERON:0003454	76.46	gold quality
intestine	UBERON:0000160	75.88	gold quality
colon	UBERON:0001155	74.28	gold quality
skeletal muscle tissue	UBERON:0001134	73.58	gold quality
muscle tissue	UBERON:0002385	70.00	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.58	gold quality
right frontal lobe	UBERON:0002810	66.48	gold quality
superior frontal gyrus	UBERON:0002661	66.24	gold quality
frontal cortex	UBERON:0001870	65.74	gold quality
prefrontal cortex	UBERON:0000451	65.25	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.17	gold quality
body of stomach	UBERON:0001161	64.93	gold quality
stomach	UBERON:0000945	64.22	gold quality
tonsil	UBERON:0002372	64.13	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.71	gold quality
anterior cingulate cortex	UBERON:0009835	63.42	gold quality
cerebral cortex	UBERON:0000956	63.26	gold quality
liver	UBERON:0002107	62.90	gold quality
muscle of leg	UBERON:0001383	62.51	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.84	gold quality
gastrocnemius	UBERON:0001388	61.62	gold quality
cortex of kidney	UBERON:0001225	61.14	gold quality
kidney	UBERON:0002113	60.61	gold quality
lung	UBERON:0002048	60.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.54

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.