PPEF1-AS1

Summary

PPEF1-AS1 (PPEF1 antisense RNA 1, HGNC:40463) is a long non-coding RNA gene on chromosome Xp22.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40463
Approved symbol	PPEF1-AS1
Name	PPEF1 antisense RNA 1
Location	Xp22.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237221
Ensembl biotype	lncRNA
Entrez	100874004
RNAcentral	URS000075D706 — lncRNA, 492 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000430641, ENST00000824990

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430641 — 2 exons

Exon	Start	End
ENSE00001685408	18688643	18688905
ENSE00001698902	18691438	18691604

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 79.71.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.71	silver quality
monocyte	CL:0000576	65.39	gold quality
bone marrow cell	CL:0002092	60.35	silver quality
prefrontal cortex	UBERON:0000451	58.88	gold quality
bone marrow	UBERON:0002371	58.55	gold quality
cortex of kidney	UBERON:0001225	53.01	silver quality
blood	UBERON:0000178	52.50	gold quality
superior frontal gyrus	UBERON:0002661	51.49	gold quality
gastrocnemius	UBERON:0001388	50.63	gold quality
endometrium	UBERON:0001295	50.31	silver quality
body of pancreas	UBERON:0001150	50.07	gold quality
frontal cortex	UBERON:0001870	49.93	gold quality
anterior cingulate cortex	UBERON:0009835	49.57	gold quality
substantia nigra	UBERON:0002038	49.45	gold quality
endocervix	UBERON:0000458	49.27	gold quality
left coronary artery	UBERON:0001626	49.16	gold quality
cerebellar hemisphere	UBERON:0002245	48.45	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.43	gold quality
cerebral cortex	UBERON:0000956	48.39	gold quality
tonsil	UBERON:0002372	48.27	gold quality
left adrenal gland	UBERON:0001234	48.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	48.10	gold quality
liver	UBERON:0002107	47.53	silver quality
tibial artery	UBERON:0007610	47.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	46.95	gold quality
brain	UBERON:0000955	46.66	gold quality
right coronary artery	UBERON:0001625	45.24	gold quality
transverse colon	UBERON:0001157	44.99	gold quality
Ammon’s horn	UBERON:0001954	44.85	gold quality
right frontal lobe	UBERON:0002810	44.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.