PPFIA2-AS2

Summary

PPFIA2-AS2 (PPFIA2 antisense RNA 2, HGNC:58195) is a long non-coding RNA gene on chromosome 12q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58195
Approved symbol	PPFIA2-AS2
Name	PPFIA2 antisense RNA 2
Location	12q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258162
Ensembl biotype	lncRNA
Entrez	139281645
RNAcentral	URS0000EED665 — lncRNA, 3351 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000546936, ENST00000550272, ENST00000652105, ENST00000656478, ENST00000665004, ENST00000666472, ENST00000669351, ENST00000671127

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546936 — 3 exons

Exon	Start	End
ENSE00002325484	81378042	81378205
ENSE00002382614	81417298	81417339
ENSE00002384949	81430003	81431411

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 91.23.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar vermis	UBERON:0004720	91.23	gold quality
corpus callosum	UBERON:0002336	84.37	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.77	gold quality
colonic epithelium	UBERON:0000397	71.86	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.52	gold quality
skeletal muscle tissue	UBERON:0001134	67.95	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	67.36	gold quality
spinal cord	UBERON:0002240	67.35	gold quality
primary visual cortex	UBERON:0002436	66.22	gold quality
thymus	UBERON:0002370	66.14	silver quality
substantia nigra	UBERON:0002038	65.03	gold quality
calcaneal tendon	UBERON:0003701	64.21	gold quality
Ammon’s horn	UBERON:0001954	62.58	gold quality
putamen	UBERON:0001874	62.34	gold quality
amygdala	UBERON:0001876	61.61	gold quality
superior frontal gyrus	UBERON:0002661	61.49	gold quality
temporal lobe	UBERON:0001871	61.46	gold quality
cortical plate	UBERON:0005343	61.35	gold quality
ganglionic eminence	UBERON:0004023	60.90	gold quality
sural nerve	UBERON:0015488	60.74	gold quality
caudate nucleus	UBERON:0001873	60.23	gold quality
stomach	UBERON:0000945	60.00	gold quality
body of stomach	UBERON:0001161	59.39	gold quality
ventricular zone	UBERON:0003053	59.32	silver quality
prefrontal cortex	UBERON:0000451	59.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.95	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.61	gold quality
frontal cortex	UBERON:0001870	58.04	gold quality
cerebral cortex	UBERON:0000956	57.78	gold quality
brain	UBERON:0000955	56.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.