PPIC-AS1

Summary

PPIC-AS1 (PPIC antisense RNA 1, HGNC:40464) is a long non-coding RNA gene on chromosome 5q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40464
Approved symbol	PPIC-AS1
Name	PPIC antisense RNA 1
Location	5q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249996
Ensembl biotype	lncRNA
Entrez	107986447
RNAcentral	URS0002A38F4D — lncRNA, 756 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000506859, ENST00000833764, ENST00000833765

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506859 — 2 exons

Exon	Start	End
ENSE00002038330	123054463	123054667
ENSE00002067958	123036271	123036626

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 92.38.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.38	gold quality
ventricular zone	UBERON:0003053	67.06	gold quality
colonic epithelium	UBERON:0000397	65.65	silver quality
heart left ventricle	UBERON:0002084	61.58	gold quality
skeletal muscle tissue	UBERON:0001134	61.25	gold quality
right coronary artery	UBERON:0001625	61.20	gold quality
urinary bladder	UBERON:0001255	60.90	gold quality
descending thoracic aorta	UBERON:0002345	60.44	gold quality
smooth muscle tissue	UBERON:0001135	60.29	gold quality
heart	UBERON:0000948	59.94	gold quality
gall bladder	UBERON:0002110	59.38	gold quality
stromal cell of endometrium	CL:0002255	59.21	gold quality
thoracic aorta	UBERON:0001515	58.78	gold quality
lymph node	UBERON:0000029	58.67	gold quality
ascending aorta	UBERON:0001496	58.40	gold quality
duodenum	UBERON:0002114	58.34	gold quality
thyroid gland	UBERON:0002046	58.22	gold quality
left lobe of thyroid gland	UBERON:0001120	58.07	gold quality
islet of Langerhans	UBERON:0000006	57.99	gold quality
popliteal artery	UBERON:0002250	57.99	gold quality
left coronary artery	UBERON:0001626	57.95	gold quality
tibial artery	UBERON:0007610	57.94	gold quality
right lobe of thyroid gland	UBERON:0001119	57.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.53	gold quality
placenta	UBERON:0001987	57.31	gold quality
right atrium auricular region	UBERON:0006631	56.63	gold quality
liver	UBERON:0002107	55.85	gold quality
adult mammalian kidney	UBERON:0000082	55.36	gold quality
endometrium	UBERON:0001295	55.23	gold quality
kidney	UBERON:0002113	54.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.