PPM1B-DT

Summary

PPM1B-DT (PPM1B divergent transcript, HGNC:55161) is a long non-coding RNA gene on chromosome 2p21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55161
Approved symbol	PPM1B-DT
Name	PPM1B divergent transcript
Location	2p21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273106
Ensembl biotype	lncRNA
Entrez	102723904
RNAcentral	URS0002A2481D — lncRNA, 1750 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000609837, ENST00000727108, ENST00000727109, ENST00000727110, ENST00000727111, ENST00000727112, ENST00000727113, ENST00000727114, ENST00000727115, ENST00000727116, ENST00000727117

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609837 — 2 exons

Exon	Start	End
ENSE00004052305	44167580	44168859
ENSE00004052318	44166437	44166906

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 92.49.

Top tissues by expression

156 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.49	gold quality
kidney epithelium	UBERON:0004819	90.87	gold quality
upper arm skin	UBERON:0004263	87.21	gold quality
tibialis anterior	UBERON:0001385	86.37	silver quality
sperm	CL:0000019	86.01	silver quality
left ventricle myocardium	UBERON:0006566	86.00	gold quality
cardiac muscle of right atrium	UBERON:0003379	85.44	gold quality
pancreatic ductal cell	CL:0002079	84.60	silver quality
epithelial cell of pancreas	CL:0000083	83.58	gold quality
nasal cavity epithelium	UBERON:0005384	82.96	gold quality
ileal mucosa	UBERON:0000331	78.92	gold quality
superficial temporal artery	UBERON:0001614	78.29	gold quality
deltoid	UBERON:0001476	78.11	silver quality
quadriceps femoris	UBERON:0001377	77.77	gold quality
myocardium	UBERON:0002349	77.68	gold quality
vastus lateralis	UBERON:0001379	77.10	gold quality
sural nerve	UBERON:0015488	76.29	silver quality
metanephros	UBERON:0000081	75.29	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	75.14	gold quality
secondary oocyte	CL:0000655	72.08	silver quality
bone marrow	UBERON:0002371	68.37	gold quality
trabecular bone tissue	UBERON:0002483	68.24	gold quality
cerebellar vermis	UBERON:0004720	67.96	gold quality
lower lobe of lung	UBERON:0008949	66.96	silver quality
vena cava	UBERON:0004087	66.89	silver quality
upper lobe of lung	UBERON:0008948	66.70	gold quality
mucosa of paranasal sinus	UBERON:0005030	66.50	gold quality
layer of synovial tissue	UBERON:0007616	66.50	gold quality
blood	UBERON:0000178	66.09	gold quality
caecum	UBERON:0001153	65.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.