PPM1L-DT

Summary

PPM1L-DT (PPM1L divergent transcript, HGNC:55390) is a long non-coding RNA gene on chromosome 3q25.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55390
Approved symbol	PPM1L-DT
Name	PPM1L divergent transcript
Location	3q25.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260572
Ensembl biotype	lncRNA
Entrez	119863869
RNAcentral	URS00026A1F8E — lncRNA, 4667 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000566372, ENST00000748637, ENST00000748638, ENST00000748639, ENST00000748640, ENST00000748641, ENST00000748642, ENST00000748643

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000566372 — 1 exons

Exon	Start	End
ENSE00002613040	160753428	160755142

Expression profiles

Bgee: expression breadth ubiquitous, 176 present calls, max score 84.97.

Top tissues by expression

233 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.97	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.27	gold quality
gastrocnemius	UBERON:0001388	73.82	gold quality
muscle of leg	UBERON:0001383	72.25	gold quality
pituitary gland	UBERON:0000007	70.17	gold quality
islet of Langerhans	UBERON:0000006	70.04	gold quality
adenohypophysis	UBERON:0002196	69.93	gold quality
calcaneal tendon	UBERON:0003701	69.61	gold quality
ventricular zone	UBERON:0003053	67.85	gold quality
ganglionic eminence	UBERON:0004023	67.61	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.60	gold quality
right uterine tube	UBERON:0001302	66.47	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.42	gold quality
popliteal artery	UBERON:0002250	66.37	gold quality
left ovary	UBERON:0002119	66.34	gold quality
tibial artery	UBERON:0007610	66.33	gold quality
cerebellar hemisphere	UBERON:0002245	66.19	gold quality
cerebellar cortex	UBERON:0002129	66.13	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.79	gold quality
pancreas	UBERON:0001264	65.70	gold quality
parotid gland	UBERON:0001831	65.70	silver quality
tendon	UBERON:0000043	65.37	gold quality
right lobe of thyroid gland	UBERON:0001119	65.31	gold quality
right ovary	UBERON:0002118	65.27	gold quality
prefrontal cortex	UBERON:0000451	65.21	gold quality
tibial nerve	UBERON:0001323	65.12	gold quality
cerebellum	UBERON:0002037	65.12	gold quality
cortical plate	UBERON:0005343	65.11	gold quality
left lobe of thyroid gland	UBERON:0001120	64.73	gold quality
thyroid gland	UBERON:0002046	64.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.