PPP1CB-DT

Summary

PPP1CB-DT (PPP1CB divergent transcript, HGNC:55829) is a long non-coding RNA gene on chromosome 2p23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55829
Approved symbol	PPP1CB-DT
Name	PPP1CB divergent transcript
Location	2p23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226833
Ensembl biotype	lncRNA
Entrez	112267877
RNAcentral	URS0000EF661E — lncRNA, 3541 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 71 — 71 lncRNA

ENST00000428036, ENST00000444501, ENST00000452212, ENST00000653462, ENST00000658445, ENST00000659356, ENST00000659984, ENST00000662538, ENST00000663311, ENST00000665023, ENST00000666397, ENST00000668960, ENST00000669783, ENST00000686707, ENST00000757368, ENST00000757369, ENST00000757370, ENST00000757371, ENST00000757372, ENST00000757373, ENST00000757374, ENST00000757375, ENST00000757376, ENST00000757377, ENST00000757378, ENST00000757379, ENST00000757380, ENST00000757381, ENST00000757382, ENST00000757383, ENST00000757384, ENST00000757385, ENST00000757386, ENST00000757387, ENST00000757388, ENST00000757389, ENST00000757390, ENST00000757391, ENST00000757392, ENST00000757393, ENST00000757394, ENST00000757395, ENST00000757396, ENST00000757397, ENST00000757398, ENST00000757399, ENST00000757400, ENST00000757401, ENST00000757402, ENST00000757403, ENST00000757404, ENST00000757405, ENST00000757406, ENST00000757407, ENST00000757408, ENST00000757409, ENST00000757410, ENST00000757411, ENST00000757412, ENST00000757413, ENST00000757414, ENST00000757415, ENST00000757416, ENST00000757417, ENST00000757418, ENST00000757419, ENST00000757420, ENST00000757421, ENST00000757422, ENST00000757423, ENST00000757424

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428036 — 4 exons

Exon	Start	End
ENSE00001715462	28731911	28731983
ENSE00001787351	28731666	28731737
ENSE00004108435	28708260	28709499
ENSE00004108501	28736027	28736262

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 88.70.

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
descending thoracic aorta	UBERON:0002345	88.70	gold quality
ascending aorta	UBERON:0001496	88.13	gold quality
thoracic aorta	UBERON:0001515	88.13	gold quality
aorta	UBERON:0000947	85.69	gold quality
left coronary artery	UBERON:0001626	85.03	gold quality
popliteal artery	UBERON:0002250	84.18	gold quality
tibial artery	UBERON:0007610	84.17	gold quality
coronary artery	UBERON:0001621	83.03	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.85	gold quality
right coronary artery	UBERON:0001625	82.81	gold quality
apex of heart	UBERON:0002098	74.48	gold quality
colonic epithelium	UBERON:0000397	74.38	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.54	gold quality
muscle of leg	UBERON:0001383	73.38	gold quality
right uterine tube	UBERON:0001302	72.93	gold quality
tibial nerve	UBERON:0001323	72.05	gold quality
gastrocnemius	UBERON:0001388	71.98	gold quality
heart left ventricle	UBERON:0002084	71.94	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.92	gold quality
heart	UBERON:0000948	71.48	gold quality
cardiac ventricle	UBERON:0002082	70.94	gold quality
right atrium auricular region	UBERON:0006631	70.22	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	69.99	gold quality
left uterine tube	UBERON:0001303	69.97	gold quality
calcaneal tendon	UBERON:0003701	69.87	gold quality
body of uterus	UBERON:0009853	69.86	gold quality
endocervix	UBERON:0000458	69.48	gold quality
cardiac atrium	UBERON:0002081	69.46	gold quality
right lung	UBERON:0002167	69.41	gold quality
mucosa of stomach	UBERON:0001199	69.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.