PPP1R12A-AS2
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Summary
PPP1R12A-AS2 (PPP1R12A antisense RNA 2, HGNC:55456) is a long non-coding RNA gene on chromosome 12q21.2.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:55456 |
| Approved symbol | PPP1R12A-AS2 |
| Name | PPP1R12A antisense RNA 2 |
| Location | 12q21.2 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000258048 |
| Ensembl biotype | lncRNA |
| Entrez | 105369864 |
| RNAcentral | URS00026A1C78 — lncRNA, 2215 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000551995
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000551995 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002351147 | 79778351 | 79778451 |
| ENSE00002387833 | 79690144 | 79690396 |
Expression profiles
Bgee: expression breadth ubiquitous, 127 present calls, max score 84.76.
Top tissues by expression
127 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 84.76 | silver quality |
| sural nerve | UBERON:0015488 | 80.64 | gold quality |
| popliteal artery | UBERON:0002250 | 78.49 | gold quality |
| tibial artery | UBERON:0007610 | 78.43 | gold quality |
| calcaneal tendon | UBERON:0003701 | 77.10 | gold quality |
| colonic epithelium | UBERON:0000397 | 76.92 | gold quality |
| ascending aorta | UBERON:0001496 | 76.59 | gold quality |
| thoracic aorta | UBERON:0001515 | 76.38 | gold quality |
| endocervix | UBERON:0000458 | 76.27 | gold quality |
| uterine cervix | UBERON:0000002 | 75.78 | gold quality |
| bone marrow cell | CL:0002092 | 75.73 | gold quality |
| left coronary artery | UBERON:0001626 | 75.63 | gold quality |
| body of uterus | UBERON:0009853 | 75.49 | gold quality |
| urinary bladder | UBERON:0001255 | 74.83 | gold quality |
| right coronary artery | UBERON:0001625 | 74.79 | gold quality |
| myometrium | UBERON:0001296 | 74.38 | gold quality |
| ectocervix | UBERON:0012249 | 74.25 | gold quality |
| ganglionic eminence | UBERON:0004023 | 72.95 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 72.92 | gold quality |
| left uterine tube | UBERON:0001303 | 72.77 | gold quality |
| stromal cell of endometrium | CL:0002255 | 72.45 | gold quality |
| left ovary | UBERON:0002119 | 71.80 | gold quality |
| right ovary | UBERON:0002118 | 71.74 | gold quality |
| vagina | UBERON:0000996 | 71.71 | gold quality |
| ovary | UBERON:0000992 | 71.57 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 71.36 | gold quality |
| lower esophagus | UBERON:0013473 | 70.87 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 70.86 | gold quality |
| subcutaneous adipose tissue | UBERON:0002190 | 70.82 | gold quality |
| ventricular zone | UBERON:0003053 | 70.81 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.87 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): genitourinary and/or brain malformation syndrome