PPP1R15B-AS1

Summary

PPP1R15B-AS1 (PPP1R15B and PIK3C2B antisense RNA 1, HGNC:55838) is a long non-coding RNA gene on chromosome 1q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55838
Approved symbol	PPP1R15B-AS1
Name	PPP1R15B and PIK3C2B antisense RNA 1
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL606489.1
Ensembl gene	ENSG00000226330
Ensembl biotype	lncRNA
Entrez	122455336
RNAcentral	URS0002A6C8C7 — lncRNA, 1224 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000443515, ENST00000775926, ENST00000775927, ENST00000775928, ENST00000775929, ENST00000775930, ENST00000775931, ENST00000775932

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443515 — 3 exons

Exon	Start	End
ENSE00001648362	204435337	204435461
ENSE00001681262	204435632	204435846
ENSE00001727656	204377850	204377995

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 79.08.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	79.08	gold quality
corpus callosum	UBERON:0002336	74.89	gold quality
sural nerve	UBERON:0015488	74.28	gold quality
lower esophagus mucosa	UBERON:0035834	73.06	gold quality
duodenum	UBERON:0002114	70.24	gold quality
rectum	UBERON:0001052	69.98	gold quality
skeletal muscle tissue	UBERON:0001134	69.63	gold quality
esophagus mucosa	UBERON:0002469	68.70	gold quality
metanephros cortex	UBERON:0010533	68.65	gold quality
transverse colon	UBERON:0001157	68.21	gold quality
cortical plate	UBERON:0005343	68.06	gold quality
skin of abdomen	UBERON:0001416	68.04	gold quality
small intestine	UBERON:0002108	67.61	gold quality
zone of skin	UBERON:0000014	67.48	gold quality
ventricular zone	UBERON:0003053	67.45	gold quality
lymph node	UBERON:0000029	67.32	gold quality
small intestine Peyer’s patch	UBERON:0003454	67.30	gold quality
skin of leg	UBERON:0001511	67.04	gold quality
cortex of kidney	UBERON:0001225	67.01	gold quality
muscle of leg	UBERON:0001383	66.15	gold quality
stomach	UBERON:0000945	66.05	gold quality
gastrocnemius	UBERON:0001388	65.88	gold quality
body of stomach	UBERON:0001161	65.85	gold quality
urinary bladder	UBERON:0001255	65.85	gold quality
mucosa of transverse colon	UBERON:0004991	65.48	gold quality
placenta	UBERON:0001987	65.35	gold quality
gall bladder	UBERON:0002110	65.32	gold quality
intestine	UBERON:0000160	65.17	gold quality
smooth muscle tissue	UBERON:0001135	65.12	gold quality
fundus of stomach	UBERON:0001160	64.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.