PPP1R21-DT

Summary

PPP1R21-DT (PPP1R21 divergent transcript, HGNC:55206) is a long non-coding RNA gene on chromosome 2p16.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55206
Approved symbol	PPP1R21-DT
Name	PPP1R21 divergent transcript
Location	2p16.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272663
Ensembl biotype	lncRNA
Entrez	118568827
RNAcentral	URS0002A46D27 — lncRNA, 1579 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000609028, ENST00000812117

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609028 — 1 exons

Exon	Start	End
ENSE00003706206	48440043	48440597

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 86.75.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.75	gold quality
nucleus accumbens	UBERON:0001882	74.63	gold quality
cerebellar cortex	UBERON:0002129	74.28	gold quality
cerebellar hemisphere	UBERON:0002245	74.28	gold quality
cerebellum	UBERON:0002037	74.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	74.04	gold quality
putamen	UBERON:0001874	73.99	gold quality
pituitary gland	UBERON:0000007	72.80	gold quality
adenohypophysis	UBERON:0002196	72.39	gold quality
caudate nucleus	UBERON:0001873	71.95	gold quality
primary visual cortex	UBERON:0002436	71.38	gold quality
brain	UBERON:0000955	70.79	gold quality
prefrontal cortex	UBERON:0000451	69.70	gold quality
hypothalamus	UBERON:0001898	69.47	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.36	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.28	gold quality
ventricular zone	UBERON:0003053	69.10	gold quality
islet of Langerhans	UBERON:0000006	68.83	gold quality
cerebral cortex	UBERON:0000956	68.69	gold quality
anterior cingulate cortex	UBERON:0009835	68.67	gold quality
frontal cortex	UBERON:0001870	68.59	gold quality
amygdala	UBERON:0001876	68.50	gold quality
temporal lobe	UBERON:0001871	68.46	gold quality
right uterine tube	UBERON:0001302	68.10	gold quality
testis	UBERON:0000473	68.03	gold quality
Ammon’s horn	UBERON:0001954	68.01	gold quality
substantia nigra	UBERON:0002038	67.97	gold quality
right frontal lobe	UBERON:0002810	67.69	gold quality
ganglionic eminence	UBERON:0004023	67.61	gold quality
right testis	UBERON:0004534	67.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.