PPP1R26-AS1

Summary

PPP1R26-AS1 (PPP1R26 antisense RNA 1, HGNC:48717) is a long non-coding RNA gene on chromosome 9q34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48717
Approved symbol	PPP1R26-AS1
Name	PPP1R26 antisense RNA 1
Location	9q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225361
Ensembl biotype	lncRNA
Entrez	100506599
RNAcentral	URS000075C8DA — lncRNA, 2939 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000455039, ENST00000603624, ENST00000603893, ENST00000605260, ENST00000655118, ENST00000660718, ENST00000765286, ENST00000765287, ENST00000765288, ENST00000765289, ENST00000765290

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455039 — 2 exons

Exon	Start	End
ENSE00003489300	135468172	135468709
ENSE00003641627	135480673	135480777

Expression profiles

Bgee: expression breadth ubiquitous, 186 present calls, max score 95.34.

FANTOM5 (CAGE): breadth broad, TPM avg 1.4020 / max 28.7072, expressed in 674 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103088	1.3807	666
103087	0.0213	13

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	95.34	gold quality
right uterine tube	UBERON:0001302	77.63	gold quality
fallopian tube	UBERON:0003889	77.60	gold quality
buccal mucosa cell	CL:0002336	76.22	gold quality
cortical plate	UBERON:0005343	75.84	gold quality
mucosa of transverse colon	UBERON:0004991	75.70	gold quality
rectum	UBERON:0001052	74.62	gold quality
colonic epithelium	UBERON:0000397	74.03	gold quality
metanephros cortex	UBERON:0010533	73.24	gold quality
epithelium of nasopharynx	UBERON:0001951	71.70	silver quality
cortex of kidney	UBERON:0001225	71.65	gold quality
sperm	CL:0000019	71.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.34	gold quality
pituitary gland	UBERON:0000007	71.33	gold quality
stromal cell of endometrium	CL:0002255	71.31	gold quality
transverse colon	UBERON:0001157	71.25	gold quality
adenohypophysis	UBERON:0002196	70.61	gold quality
mucosa of paranasal sinus	UBERON:0005030	70.50	silver quality
endometrium	UBERON:0001295	70.17	gold quality
prostate gland	UBERON:0002367	69.29	gold quality
adult mammalian kidney	UBERON:0000082	69.12	gold quality
metanephros	UBERON:0000081	68.77	gold quality
kidney	UBERON:0002113	68.39	gold quality
ovary	UBERON:0000992	68.35	gold quality
lower esophagus mucosa	UBERON:0035834	67.96	gold quality
right lobe of thyroid gland	UBERON:0001119	67.45	gold quality
right frontal lobe	UBERON:0002810	67.39	gold quality
anterior cingulate cortex	UBERON:0009835	67.36	gold quality
left ovary	UBERON:0002119	67.33	gold quality
right lobe of liver	UBERON:0001114	67.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.72

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression. (PMID:35064892)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.