PPP1R35-AS1

Summary

PPP1R35-AS1 (PPP1R35 antisense RNA 1, HGNC:41194) is a long non-coding RNA gene on chromosome 7q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41194
Approved symbol	PPP1R35-AS1
Name	PPP1R35 antisense RNA 1
Location	7q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000240211
Ensembl biotype	lncRNA
Entrez	101927632
RNAcentral	URS00026A253A — lncRNA, 759 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000475250, ENST00000801019, ENST00000801020, ENST00000801021, ENST00000801022, ENST00000801023

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000475250 — 2 exons

Exon	Start	End
ENSE00001913053	100436204	100436382
ENSE00001949772	100438381	100438504

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 97.02.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1933 / max 91.5703, expressed in 54 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
79985	0.0854	6
79987	0.0784	34
79984	0.0122	6
79988	0.0113	4
79986	0.0061	2

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	97.02	gold quality
right testis	UBERON:0004534	96.77	gold quality
testis	UBERON:0000473	96.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.96	gold quality
bone marrow cell	CL:0002092	78.69	gold quality
skeletal muscle tissue	UBERON:0001134	77.50	gold quality
ganglionic eminence	UBERON:0004023	76.42	gold quality
bone marrow	UBERON:0002371	76.34	gold quality
sural nerve	UBERON:0015488	75.62	silver quality
ventricular zone	UBERON:0003053	75.09	gold quality
spleen	UBERON:0002106	74.72	gold quality
urinary bladder	UBERON:0001255	73.26	gold quality
adrenal tissue	UBERON:0018303	73.04	gold quality
colonic epithelium	UBERON:0000397	72.98	gold quality
monocyte	CL:0000576	71.75	gold quality
superior frontal gyrus	UBERON:0002661	71.75	gold quality
tonsil	UBERON:0002372	71.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.47	gold quality
endometrium	UBERON:0001295	71.40	gold quality
mucosa of transverse colon	UBERON:0004991	70.66	gold quality
right lobe of thyroid gland	UBERON:0001119	70.13	gold quality
placenta	UBERON:0001987	69.15	gold quality
thyroid gland	UBERON:0002046	68.80	gold quality
left adrenal gland cortex	UBERON:0035825	68.53	gold quality
adrenal gland	UBERON:0002369	68.46	gold quality
left lobe of thyroid gland	UBERON:0001120	68.27	gold quality
right adrenal gland cortex	UBERON:0035827	68.25	gold quality
prefrontal cortex	UBERON:0000451	68.18	gold quality
granulocyte	CL:0000094	68.08	gold quality
prostate gland	UBERON:0002367	67.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.