PPP2R2B-AS2

Summary

PPP2R2B-AS2 (PPP2R2B antisense RNA 2, HGNC:58421) is a long non-coding RNA gene on chromosome 5q32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58421
Approved symbol	PPP2R2B-AS2
Name	PPP2R2B antisense RNA 2
Location	5q32
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTB-99A3.1
Ensembl gene	ENSG00000250407
Ensembl biotype	lncRNA
Entrez	105378215

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000512730, ENST00000807433

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512730 — 4 exons

Exon	Start	End
ENSE00002020533	146563226	146563471
ENSE00002047226	146607694	146607817
ENSE00002055964	146606969	146607220
ENSE00004201495	146616936	146617383

Expression profiles

Bgee: expression breadth broad, 67 present calls, max score 63.75.

Top tissues by expression

67 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
kidney	UBERON:0002113	63.75	silver quality
placenta	UBERON:0001987	58.67	gold quality
corpus callosum	UBERON:0002336	58.47	gold quality
monocyte	CL:0000576	57.37	gold quality
ganglionic eminence	UBERON:0004023	55.41	silver quality
urinary bladder	UBERON:0001255	54.47	gold quality
calcaneal tendon	UBERON:0003701	52.35	silver quality
blood	UBERON:0000178	52.18	gold quality
muscle tissue	UBERON:0002385	51.96	gold quality
prefrontal cortex	UBERON:0000451	51.85	gold quality
right hemisphere of cerebellum	UBERON:0014890	50.39	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.49	gold quality
muscle of leg	UBERON:0001383	48.98	silver quality
primary visual cortex	UBERON:0002436	47.17	silver quality
islet of Langerhans	UBERON:0000006	47.11	gold quality
gastrocnemius	UBERON:0001388	46.99	silver quality
superior frontal gyrus	UBERON:0002661	46.31	silver quality
adipose tissue	UBERON:0001013	45.87	gold quality
tibial artery	UBERON:0007610	45.83	gold quality
cerebellar hemisphere	UBERON:0002245	45.01	silver quality
cerebral cortex	UBERON:0000956	44.94	gold quality
fallopian tube	UBERON:0003889	44.34	gold quality
multicellular organism	UBERON:0000468	44.29	gold quality
brain	UBERON:0000955	43.98	silver quality
adrenal tissue	UBERON:0018303	43.80	silver quality
subcutaneous adipose tissue	UBERON:0002190	43.77	gold quality
heart	UBERON:0000948	42.96	silver quality
ascending aorta	UBERON:0001496	42.91	silver quality
heart left ventricle	UBERON:0002084	42.89	silver quality
colon	UBERON:0001155	42.75	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.