PPP3CA-DT

Summary

PPP3CA-DT (PPP3CA divergent transcript, HGNC:58118) is a long non-coding RNA gene on chromosome 4q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58118
Approved symbol	PPP3CA-DT
Name	PPP3CA divergent transcript
Location	4q24
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ20021, SRSP, FLJ
Ensembl gene	ENSG00000254531
Ensembl biotype	lncRNA
Entrez	90024
RNAcentral	URS000075C47F — lncRNA, 810 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000527564, ENST00000529296, ENST00000689482, ENST00000750060

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527564 — 2 exons

Exon	Start	End
ENSE00004094155	101348324	101349097
ENSE00004094157	101347733	101348009

Expression profiles

Bgee: expression breadth ubiquitous, 239 present calls, max score 94.69.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.7492 / max 45.9958, expressed in 1693 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
49030	5.6407	1643
49031	2.1085	1061

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vena cava	UBERON:0004087	94.69	gold quality
tendon of biceps brachii	UBERON:0008188	92.99	gold quality
pancreatic ductal cell	CL:0002079	91.43	silver quality
kidney epithelium	UBERON:0004819	89.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.76	gold quality
pons	UBERON:0000988	88.75	gold quality
buccal mucosa cell	CL:0002336	88.62	silver quality
prefrontal cortex	UBERON:0000451	88.40	gold quality
cartilage tissue	UBERON:0002418	88.35	gold quality
nipple	UBERON:0002030	87.99	gold quality
nucleus accumbens	UBERON:0001882	87.95	gold quality
trachea	UBERON:0003126	87.89	gold quality
parotid gland	UBERON:0001831	87.82	gold quality
prostate gland	UBERON:0002367	87.35	gold quality
putamen	UBERON:0001874	87.23	gold quality
Brodmann (1909) area 9	UBERON:0013540	87.20	gold quality
pericardium	UBERON:0002407	87.12	gold quality
caudate nucleus	UBERON:0001873	86.70	gold quality
cardia of stomach	UBERON:0001162	86.40	gold quality
frontal cortex	UBERON:0001870	85.98	gold quality
saphenous vein	UBERON:0007318	85.69	gold quality
pharyngeal mucosa	UBERON:0000355	85.61	silver quality
left ventricle myocardium	UBERON:0006566	85.45	gold quality
amniotic fluid	UBERON:0000173	85.42	gold quality
anterior cingulate cortex	UBERON:0009835	85.38	gold quality
neocortex	UBERON:0001950	85.33	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.23	gold quality
right frontal lobe	UBERON:0002810	85.21	gold quality
cerebellar vermis	UBERON:0004720	85.20	silver quality
pylorus	UBERON:0001166	85.15	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.